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    Academic Journals

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• Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System

  Authors:Kangyi Zhang, Qilong Wang, Qiuxuan Yang, Qiuyu Wei, Na Man, Michael Adu-Frimpong, et al.From:AAPS PharmSciTech (Vol. 20, Issue 5) Peer-Reviewed

  July 2019336 words Report

   Abstract Only

• Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

  Authors:Kotaro Shirakawa, Lan Wang, Na Man, Jasna Maksimoska, Alexander W Sorum, Hyung W Lim, et al.From:eLife (Vol. 5) Peer-Reviewed

  May 31, 201613,139 words Report 1530LSalicylate and acetylsalicylic acid are potent and widely used anti-inflammatory drugs. They are thought to exert their therapeutic effects through multiple mechanisms, including the inhibition of cyclo-oxygenases,...

• Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis

  Authors:Fan Liu, Guoyan Cheng, Pierre-Jacques Hamard, Sarah Greenblatt, Lan Wang, Na Man, et al.From:Journal of Clinical Investigation (Vol. 125, Issue 9) Peer-Reviewed

  Sept. 20156,374 words Report 1500LEpigenetic regulators play critical roles in normal hematopoiesis, and the activity of these enzymes is frequently altered in hematopoietic cancers. The major type II protein arginine methyltransferase PRMT5 catalyzes...

• Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy

  Authors:Peng Zhang, Fuhong He, Jie Bai, Shohei Yamamoto, Shi Chen, Lin Zhang, et al.From:Journal of Clinical Investigation (Vol. 128, Issue 12) Peer-Reviewed

  Dec. 201810,624 words Report 1450LASXL1 is frequently mutated in myeloid malignancies and is known to co-occur with other gene mutations. However, the molecular mechanisms underlying the leukemogenesis associated with ASXL1 and cooperating mutations...

• Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.

  Authors:Na Liu, Junhong Song, Yangyang Xie, Xiao-Lin Wang, Bowen Rong, Na Man, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 116, Issue 3) Peer-Reviewed

  Jan. 15, 201910,661 words Report 1470L

   Abstract Only