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From:PLoS ONE (Vol. 10, Issue 12) Peer-ReviewedBackground The AKT/mTORC1/S6K pathway is frequently overstimulated in breast cancer, constituting a promising therapeutic target. The benefit from mTOR inhibitors varies, likely as a consequence of tumour...
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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Susann Busch 1 , Lisa Rydén 2 , Olle Stål 3 , Karin Jirström 4 , Göran Landberg 1 , 4 , 5 , * Introduction The administration of the anti-estrogen tamoxifen is an adjuvant endocrine therapy for patients...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Tove Sivik 1 , * , Cecilia Gunnarsson 2 , 3 , Tommy Fornander 4 , Bo Nordenskjöld 1 , 3 , Lambert Skoog 4 , Olle Stål 1 , 3 , Agneta Jansson 1 Introduction Peripheral intracrine sex steroid synthesis...