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    Academic Journals

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• The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways.

  Authors:Seth A. Domfeh, Patrick W. Narkwa, Osbourne Quaye, Kwadwo A. Kusi, Bright S. Addy, Sian Lant, et al.From:Journal of Immunology Research (Vol. 2022) Peer-Reviewed

  July 26, 20227,967 words Article 1300LType 1 interferons (IFN-1) are pleiotropic cytokines with well-established anticancer and antiviral properties, particularly in mucosal tissues. Hence, natural IFN-1-inducing treatments are highly sought after in the...

• Occurrence of influenza and bacterial infections in cancer patients receiving radiotherapy in Ghana.

  Authors:Augustina K. Arjarquah, Evangeline Obodai, Hannah Ayettey Anie, Michael Aning Osei, John Kofi Odoom, Joseph H. K. Bonney, et al.From:PLoS ONE (Vol. 17, Issue 7) Peer-Reviewed

  July 26, 20227,225 words Report 1550LBackground Influenza co-infection with bacteria is a leading cause of influenza-related deaths and severe respiratory infections, especially among high-risk groups like cancer patients undergoing treatment. However,...

• Circulation of hepatitis delta virus and occult hepatitis B virus infection amongst HIV/HBV co-infected patients in Korle-Bu, Ghana.

  Authors:Keren Attiku, Joseph Bonney, Esinam Agbosu, Evelyn Bonney, Peter Puplampu, Vincent Ganu, et al.From:PLoS ONE (Vol. 16, Issue 1) Peer-Reviewed

  Jan. 7, 20215,362 words Report 1610LBackground Within HIV/HBV infected patients, an increase in HDV infection has been observed; there is inadequate information on HDV prevalence as well as virologic profile in Ghana. This study sought to determine the...

• Effectiveness of monovalent and pentavalent rotavirus vaccine

  Authors:Margaret M. Cortese, Lilly Cheng Immergluck, Melissa Held, Shabnam Jain, Trisha Chan, Alexandra P. Grizas, et al.From:Pediatrics (Vol. 132, Issue 1) Peer-Reviewed

  July 2013 Report

   Citation Only

• Rotavirus G9P[4] in 3 countries in Latin America, 2009-2010

  Authors:Osbourne Quaye, Sharla McDonald, Mathew D. Esona, Freda C. Lyde, Slavica Mijatovic-Rustempasic, Sunando Roy, et al.From:Emerging Infectious Diseases (Vol. 19, Issue 8) Peer-Reviewed

  Aug. 20131,334 words Article 1310LTo the Editor: Group A rotaviruses are the most common viral cause of acute gastroenteritis in young children. The most frequently detected group A rotavirus genotype combinations include G1P[8], G2P[4], G3P[8], G4P[8],...

• Role of Glu312 in binding and positioning of the substrate for the hydride transfer reaction in choline oxidase

  Authors:Osbourne Quaye, George T. Lountos, Fan Fan, Allen M. Orville, and Giovanni GaddaFrom:Biochemistry (Vol. 47, Issue 1) Peer-Reviewed

  Jan. 8, 200841 words Article

   Abstract Only

• Impact of malaria and hepatitis B co-infection on clinical and cytokine profiles among pregnant women.

  Authors:Nsoh Godwin Anabire, Paul Armah Aryee, Abass Abdul-Karim, Osbourne Quaye, Gordon Akanzuwine Awandare, and Gideon Kofi HelegbeFrom:PLoS ONE (Vol. 14, Issue 4) Peer-Reviewed

  Apr. 19, 20195,023 words Report 1500LBackground The overlap of malaria and chronic hepatitis B (CHB) is common in endemic regions, however, it is not known if this co-infection could adversely influence clinical and immunological responses. This study...

• Prevalence of malaria and hepatitis B among pregnant women in Northern Ghana: Comparing RDTs with PCR

  Authors:Nsoh Godwin Anabire, Paul Armah Aryee, Abass Abdul-Karim, Issah Bakari Abdulai, Osbourne Quaye, Gordon Akanzuwine Awandare, et al.From:PLoS ONE (Vol. 14, Issue 2) Peer-Reviewed

  Feb. 6, 20196,008 words Report 1480LBackground High prevalence of malaria and hepatitis B has been reported among pregnant women in Ghana. In endemic areas, the diagnoses of malaria and hepatitis B among pregnant women on antenatal visits are done...

• Two rotavirus outbreaks caused by genotype G2P[4] at large retirement communities: cohort studies

  Authors:Cristina V. Cardemil, Margaret M. Cortese, Andrew Medina-Marino, Supriya Jasuja, Rishi Desai, Jessica Leung, et al.From:Annals of Internal Medicine (Vol. 157, Issue 9) Peer-Reviewed

  Nov. 6, 2012 Author abstract, Rep...

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• High resistance to reverse transcriptase inhibitors among persons infected with human immunodeficiency virus type 1 subtype circulating recombinant form 02_AG in Ghana and on antiretroviral therapy

  Authors:Selase D. Deletsu, Edward K. Maina, Osbourne Quaye, William K. Ampofo, Gordon A. Awandare, and Evelyn Y. BonneyFrom:Medicine (Vol. 99, Issue 7) Peer-Reviewed

  Feb. 2020446 words Author abstract, Rep...

   Abstract Only

• Helicobacter Pylori Variants with ABC-Type Tyrosine Phosphorylation Motif in Gastric Biopsies of Ghanaian Patients.

  Authors:Emmanuel A. Tagoe, Gordon A. Awandare, Osbourne Quaye, Richard H. Asmah, Timothy N. Archampong, Mahasin A. Osman, et al.From:BioMed Research International (Vol. 2021) Peer-Reviewed

  Mar. 31, 20215,108 words Report 1520LBackground. Helicobacter pylori pathogenicity and disease severity are determined by the tyrosine phosphorylation motifs of CagA protein. This study is aimed at detecting the presence of H. pylori and identifying the...

• The Current State of Parkinsonism in West Africa: A Systematic Review.

  Authors:Jude T. Quarshie, Esther N. Mensah, Osbourne Quaye, and Anastasia R. AikinsFrom:Parkinson's Disease (Vol. 2021) Peer-Reviewed

  Sept. 30, 20217,851 words Article 1200LParkinsonism is one of the most common neurodegenerative diseases among the elderly. Africa is experiencing an increasing burden of age-related conditions including parkinsonism. However, there is not enough data on the...

• Effectiveness of monovalent and pentavalent rotavirus vaccines in Guatemala

  Authors:Paul A. Gastanaduy, Ingrid Contreras-Roldan, Chris Bernart, Beatriz Lopez, Stephen R. Benoit, Marvin Xuya, et al.From:Clinical Infectious Diseases (Vol. 62, Issue 9) Peer-Reviewed

  May 1, 2016 Report

   Citation Only

• Imbalance of antioxidant enzymes activities and trace elements levels in Ghanaian HIV-infected patients

  Authors:Osbourne Quaye, Joshua Agbemefa Kuleape, Evelyn Yayra Bonney, Peter Puplampu, and Emmanuel Ayitey TagoeFrom:PLoS ONE (Vol. 14, Issue 7) Peer-Reviewed

  July 24, 20195,251 words Report 1550LHuman immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) have been associated with high oxidative stress in HIV patients. The disparity in antioxidant-oxidant levels in HIV patients favours viral...

• One-step multiplex real-time RT-PCR assay for detecting and genotyping wild-type group A rotavirus strains and vaccine strains (Rotarix[R] and RotaTeq[R]) in stool samples

  Authors:Rashi Gautam, Slavica Mijatovic-Rustempasic, Mathew D. Esona, Ka Ian Tam, Osbourne Quaye, and Michael D. BowenFrom:PeerJ (Vol. 4) Peer-Reviewed

  Jan. 11, 201610,971 words Article 1500LBackground. Group A rotavirus (RVA) infection is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live-attenuated rotavirus vaccines, RotaTeq® and Rotarix®, has...

• Homozygous deletion of both GSTM1 and GSTT1 genes is associated with higher CD4.sup.+ T cell counts in Ghanaian HIV patients

  Authors:Joshua Agbemefa Kuleape, Emmanuel Ayitey Tagoe, Peter Puplampu, Evelyn Yayra Bonney, and Osbourne QuayeFrom:PLoS ONE (Vol. 13, Issue 5) Peer-Reviewed

  May 24, 20184,625 words Report 1550LGlutathione S-transferase (GST) family of enzymes are involved in a two-stage detoxification process of a wide range of environmental toxins, carcinogens and xenobiotics. The GST enzymes play important roles in...