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From:PLoS ONE (Vol. 16, Issue 12) Peer-ReviewedA high genetic load can negatively affect population viability and increase susceptibility to diseases and other environmental stressors. Prior microsatellite studies of two African buffalo (Syncerus caffer) populations...
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From:PLoS ONE (Vol. 10, Issue 10) Peer-ReviewedThe evolutionary history of a species is key for understanding the taxonomy and for the design of effective management strategies for species conservation. The knowledge about the phylogenetic position of the lion...
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From:PLoS ONE (Vol. 13, Issue 2) Peer-ReviewedAuthor(s): Pim van Hooft 1,2,*, Eric R. Dougherty 3, Wayne M. Getz 3,4, Barend J. Greyling 2,5, Bas J. Zwaan 6, Armanda D. S. Bastos 2 Introduction Primary (at conception) and secondary (at birth) sex-ratio...
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From:PLoS ONE (Vol. 2, Issue 10) Peer-ReviewedSelection coefficients at the mammalian Y chromosome typically do not deviate strongly from neutrality. Here we show that strong balancing selection, maintaining intermediate frequencies of DNA sequence variants, acts...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedAuthor(s): Rudy M. Jonker 1 , 2 , * , Qiong Zhang 1 , 3 , Pim Van Hooft 1 , Maarten J. J. E. Loonen 4 , Henk P. Van der Jeugd 5 , Richard P. M. A. Crooijmans 6 , Martien A. M. Groenen 6 , Herbert H. T. Prins 1 , Robert...
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From:PLoS ONE (Vol. 14, Issue 9) Peer-ReviewedBovine tuberculosis (BTB) is endemic to the African buffalo (Syncerus caffer) of Hluhluwe-iMfolozi Park (HiP) and Kruger National Park, South Africa. In HiP, the disease has been actively managed since 1999 through a...
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From:PLoS ONE (Vol. 8, Issue 2) Peer-ReviewedAuthor(s): Nathalie Smitz 1 , * , Cécile Berthouly 2 , Daniel Cornélis 2 , Rasmus Heller 3 , Pim Van Hooft 4 , Philippe Chardonnet 5 , Alexandre Caron 2 , 6 , 7 , Herbert Prins 8 , Bettine Jansen van Vuuren 9 , Hans De...
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From:PLoS ONE (Vol. 9, Issue 11) Peer-ReviewedAlthough generally rare, deleterious alleles can become common through genetic drift, hitchhiking or reductions in selective constraints. Here we present a possible new mechanism that explains the attainment of high...