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From:Neural Regeneration Research (Vol. 16, Issue 10) Peer-ReviewedByline: Long. Ma, Jing-Yuan. Tang, Jin-Yong. Zhou, Chen. Zhu, Xin. Zhang, Ping. Zhou, Qiu. Yu, Yan. Wang, Xiao-Jian. Gu After spinal cord injury, the upward conduction of the spinal cord is lost, resulting in the loss...
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From:Nature Medicine (Vol. 7, Issue 5) Peer-ReviewedAbnormal accumulation of the amyloid-[beta] peptide (A[beta]) in the brain appears crucial to pathogenesis in all forms of Alzheimer disease (AD), but the underlying mechanisms in the sporadic forms of AD remain...
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From:Journal of Occupational and Environmental Medicine (Vol. 51, Issue 5) Peer-ReviewedCitation Only
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From:Nature (Vol. 404, Issue 6776) Peer-ReviewedAuthor(s): Jacob Raber (corresponding author) [1, 4]; Derek Wong [1]; Gui-Qiu Yu [1]; Manuel Buttini [1, 4]; Robert W. Mahley [1, 2, 3, 5]; Robert E. Pitas [1, 2, 5]; Lennart Mucke [1, 4, 6] Key proteins implicated...
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From:PLoS ONE (Vol. 9, Issue 12) Peer-ReviewedObjective Because reduction of the microtubule-associated protein Tau has beneficial effects in mouse models of Alzheimer's disease and epilepsy, we wanted to determine whether this strategy can also improve the...
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From:Nature (Vol. 469, Issue 7328) Peer-ReviewedAmyloid-[beta] oligomers may cause cognitive deficits in Alzheimer's disease by impairing neuronal NMDA-type glutamate receptors, whose function is regulated by the receptor tyrosine kinase EphB2. Here we show that...
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From:PLoS ONE (Vol. 14, Issue 12) Peer-ReviewedIn quantitative real-time PCR (qRT-PCR), data are normalized using reference genes, which helps to control for internal differences and reduce error among samples. In this study, the expression profiles of eight...
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From:BioMed Research International (Vol. 2017) Peer-ReviewedHIV prevalence is still rapidly increasing among Chinese men who have sex with men (MSM). The Internet also makes it easier for MSM to have casual partners. This study aims to evaluate the trend of Internet- based...
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From:Evidence - Based Complementary and Alternative Medicine (Vol. 2020) Peer-ReviewedHerb-pairs are the basic units of composition in Chinese herbal formulae, where the bridge linking Chinese medicine and prescription consists of two Chinese medicine herbs. The Suanzaoren-Wuweizi herb-pair (SWHP) is...
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From:PLoS ONE (Vol. 7, Issue 4) Peer-ReviewedBPR0L075 [6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole] is a novel anti-microtubule drug with anti-tumor and anti-angiogenic activities in vitro and in vivo. Securin is required for genome stability, and is...