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    Academic Journals

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• Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease

  Authors:Rajiv Khanna, Scott Bell, Martina Sherritt, Andrew Galbraith, Scott R. Burrows, Lee Rafter, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 96, Issue 18) Peer-Reviewed

  Aug. 31, 1999217 words Article

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• Induction of Pluripotent Protective Immunity Following Immunisation with a Chimeric Vaccine against Human Cytomegalovirus

  Authors:Jie Zhong, Michael Rist, Leanne Cooper, Corey Smith, and Rajiv KhannaFrom:PLoS ONE (Vol. 3, Issue 9) Peer-Reviewed

  Sept. 22, 20089,030 words Article 1650LBased on the life-time cost to the health care system, the Institute of Medicine has assigned the highest priority for a vaccine to control human cytomegalovirus (HCMV) disease in transplant patients and new born...

• Vaccine strategies against human cytomegalovirus infection

  Authors:Jie Zhong and Rajiv KhannaFrom:Expert Review of Anti-infective Therapy (Vol. 5, Issue 3) Peer-Reviewed

  June 20078,601 words Report Author(s): Jie Zhong 1 , Rajiv Khanna [[dagger]] 2 Keywords: congenital infection; human cytomegalovirus; immunization; vaccine Importance of human cytomegalovirus vaccine Human cytomegalovirus (HCMV;...

• Autologous CMV-specific T cells are a safe adjuvant immunotherapy for primary glioblastoma multiforme

  Authors:Corey Smith, Katie E. Lineburg, J. Paulo Martins, George R. Ambalathingal, Michelle A. Neller, Beth Morrison, et al.From:Journal of Clinical Investigation (Vol. 130, Issue 11) Peer-Reviewed

  Nov. 20206,872 words Report 1460LBACKGROUND. The recent failure of checkpoint-blockade therapies for glioblastoma multiforme (GBM) in late-phase clinical trials has directed interest toward adoptive cellular therapies (ACTs). In this open-label,...

• Hsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism

  Authors:Xiaoping Sun, Elizabeth A. Barlow, Shidong Ma, Stacy R. Hagemeier, Sarah J. Duellman, Richard R. Burgess, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 107, Issue 7) Peer-Reviewed

  Feb. 16, 2010152 words Author abstract, Rep...

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• T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response.

  Authors:Corey Smith, Dillon Corvino, Leone Beagley, Sweera Rehan, Michelle A. Neller, Pauline Crooks, et al.From:Journal of Clinical Investigation (Vol. 129, Issue 11) Peer-Reviewed

  Nov. 20197,310 words Article 1480LBACKGROUND. Impaired T cell immunity in transplant recipients is associated with infection-related morbidity and mortality. We recently reported the successful use of adoptive T cell therapy (ACT) against...

• Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

  Authors:Maher K. Gandhi and Rajiv KhannaFrom:The Lancet Infectious Diseases (Vol. 4, Issue 12) Peer-Reviewed

  Dec. 2004159 words Report

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• Recent advances in designing an effective vaccine to prevent cytomegalovirus-associated clinical diseases

  Authors:Vijayendra Dasari, Corey Smith, and Rajiv KhannaFrom:Expert Review of Vaccines (Vol. 12, Issue 6) Peer-Reviewed

  June 201311,984 words Report 1630LAuthor(s): Vijayendra Dasari 1 , Corey Smith 1 , Rajiv Khanna [*] 2 Keywords : antibody; congenital infection; epitopes; herpes virus; human cytomegalovirus; prevention of CMV disease; prophylactic vaccine; T...

• Epstein-Barr virus-specific adoptive immunotherapy: a new horizon for multiple sclerosis treatment?

  Authors:Michael P Pender and Rajiv KhannaFrom:Immunotherapy (Vol. 6, Issue 6) Peer-Reviewed

  June 20142,385 words Editorial 2010LAuthor(s): Michael P Pender aff1 aff2 aff3 , Rajiv Khanna aff1 aff3 Keywords: adoptive immunotherapy; B cell; CD8 T cell; Epstein-Barr virus; multiple sclerosis; treatment Multiple sclerosis (MS) is a common...

• Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

  Authors:Maher K Gandhi and Rajiv KhannaFrom:The Lancet Infectious Diseases (Vol. 4, Issue 12) Peer-Reviewed

  Dec. 2004197 words Article

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• Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

  Authors:Scott R. Burrows, Zhenjun Chen, Julia K. Archbold, Fleur E. Tynan, Travis Beddoe, Lars Kjer-Nielsen, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 107, Issue 23) Peer-Reviewed

  June 8, 2010209 words Author abstract

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• Heterologous prime-boost vaccination protects against EBV antigen-expressing lymphomas

  Authors:Julia Ruhl, Carmen Citterio, Christine Engelmann, Tracey Haigh, Andrzej Dzionek, Johannes Dreyer, et al.From:Journal of Clinical Investigation (Vol. 129, Issue 5) Peer-Reviewed

  May 201911,598 words Report 1510LThe Epstein-Barr virus (EBV) is one of the predominant tumor viruses in humans, but so far no therapeutic or prophylactic vaccination against this transforming pathogen is available. We demonstrated that heterologous...

• Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: implications for molecular mimicry in autoimmune disease

  Authors:Ihor S. Misko, Simone M. Cross, Rajiv Khanna, Suzanne L. Elliottt, Christopher Schmidt, Stephanie J. Pye, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 96, Issue 5) Peer-Reviewed

  Mar. 2, 1999204 words Article

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• Epstein-Barr Virus Associated Modulation of Wnt Pathway Is Not Dependent on Latent Membrane Protein-1

  Authors:Natasha Webb, Geoff Connolly, Judy Tellam, Alpha S. Yap, and Rajiv KhannaFrom:PLoS ONE (Vol. 3, Issue 9) Peer-Reviewed

  Sept. 22, 20084,341 words Article 1490LPrevious studies have indicated that Epstein-Barr virus (EBV) can modulate the Wnt pathway in virus-infected cells and this effect is mediated by EBV-encoded oncogene latent membrane protein 1 (LMP1). Here we have...

• Adoptive therapy for EBV-induced cancers: driving success with post-transplant lymphoproliferative disorder to other EBV-derived tumors

  Authors:Corey Smith and Rajiv KhannaFrom:Immunotherapy (Vol. 7, Issue 5) Peer-Reviewed

  May 20157,660 words Report 2150LAuthor(s): Corey Smith aff1 , Rajiv Khanna [*] aff1 Keywords: adoptive immunotherapy; EBV; NPC; PTLD; T cells Epstein-Barr virus infection & gene expression Epstein-Barr virus (EBV) infection is ubiquitous...

• Regulation of protein translation through mRNA structure influences MHC class 1 loading and T cell recognition

  Authors:Judy Tellam, Corey Smith, Michael Rist, Natasha Webb, Leanne Cooper, Tony Vuocolo, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 105, Issue 27) Peer-Reviewed

  July 8, 2008182 words Author abstract

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• Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: implications for vaccine design

  Authors:Scott A. Thomson, Rajiv Khanna, Joy Gardner, Scott R. Burrows, Barbara Coupar, and Denis J. MossFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 92, Issue 13) Peer-Reviewed

  June 20, 199575 words Article

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• Developing immunotherapeutic strategies for the control of Epstein-Barr virus -- associated malignancies

  Authors:Denis J. Moss, Rajiv Khanna, Martina Sherritt, Suzanne L. Elliott, and Scott R. BurrowsFrom:Journal of Acquired Immune Deficiency Syndromes (1999) (Vol. 21, Issue 4) Peer-Reviewed

  Aug. 1, 199958 words Article

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• Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV[R] Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications

  Authors:Siok-Keen Tey, Glen A. Kennedy, Deborah Cromer, Miles P. Davenport, Susan Walker, Linda I. Jones, et al.From:PLoS ONE (Vol. 8, Issue 10) Peer-Reviewed

  Oct. 11, 20135,301 words Clinical report 1310LThe reconstitution of anti-viral cellular immunity following hematopoietic stem cell transplantation (HSCT) is crucial in preventing cytomegalovirus (CMV)-associated complications. Thus immunological monitoring has...

• Prolonged illness after infectious mononucleosis is associated with altered immunity but not with increased viral load

  Authors:Barbara Cameron, Mandvi Bharadwaj, Jacqueline Burrows, Chrysa Fazou, Denis Wakefield, Ian Hickie, et al.From:Journal of Infectious Diseases (Vol. 193, Issue 5) Peer-Reviewed

  Mar. 1, 2006 Article

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