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From:Journal of Psychiatry and Neuroscience (Vol. 42, Issue 5) Peer-ReviewedBackground: There is only limited agreement with respect to location, directionality and functional implications of brain structural alterations observed in patients with schizophrenia. Additionally, their link to...
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From:Journal of Psychiatry and Neuroscience (Vol. 35, Issue 3) Peer-ReviewedWe read with great interest the article by Witthaus and colleagues (1) recently published in the Journal of Psychiatry and Neuroscience. The authors found that, compared with controls, patients at ultra-high risk (UHR)...
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From:Journal of Psychiatry and Neuroscience (Vol. 39, Issue 4) Peer-ReviewedBackground: Recent evidence has revealed abnormal functional connectivity between the frontal and parietal brain regions during working memory processing in patients with schizophrenia and first-episode psychosis....
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From:Journal of Psychiatry and Neuroscience (Vol. 41, Issue 6) Peer-Reviewed
Dysfunctional insular connectivity during reward prediction in patients with first-episode psychosis
Background: Increasing evidence indicates that psychosis is associated with abnormal reward processing. Imaging studies in patients with first-episode psychosis (FEP) have revealed reduced activity in diverse brain...