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    Academic Journals

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• Biclustering reveals potential knee OA phenotypes in exploratory analyses: Data from the Osteoarthritis Initiative.

  Authors:Amanda E. Nelson, Thomas H. Keefe, Todd A. Schwartz, Leigh F. Callahan, Richard F. Loeser, Yvonne M. Golightly, et al.From:PLoS ONE (Vol. 17, Issue 5) Peer-Reviewed

  May 24, 20227,353 words Report 1500LObjective To apply biclustering, a methodology originally developed for analysis of gene expression data, to simultaneously cluster observations and clinical features to explore candidate phenotypes of knee...

• Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli

  Authors:Christopher B. Forsyth, Ada Cole, Gillian Murphy, Julia L. Bienias, Hee-Jeong Im, and Richard F. Loeser, Jr.From:The Journals of Gerontology, Series A (Vol. 60, Issue 9) Peer-Reviewed

  Sept. 2005127 words Author abstract

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• Cell death in osteoarthritis

  Author:Richard F. LoeserFrom:Current Rheumatology Reports (Vol. 10, Issue 1)

  Feb. 2008220 words Article

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• Inflammatory Biomarkers and Physical Function in Older, Obese Adults with Knee Pain and Self-Reported Osteoarthritis After Intensive Weight-Loss Therapy

  Authors:Gary D. Miller, Barbara J. Nicklas, and Richard F. LoeserFrom:Journal of the American Geriatrics Society (Vol. 56, Issue 4) Peer-Reviewed

  Apr. 2008311 words Clinical report

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• Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial

  Authors:Barbara J. Nicklas, Walter Ambrosius, Stephen P. Messier, Gary D. Miller, Brenda WJH Penninx, Richard F. Loeser, et al.From:American Journal of Clinical Nutrition (Vol. 79, Issue 4) Peer-Reviewed

  Apr. 2004272 words Brief article

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• Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis

  Authors:Richard F. Loeser, Amy L. Olex, Margaret A. McNulty, Cathy S. Carlson, Michael Callahan, Cristin Ferguson, et al.From:PLoS ONE (Vol. 8, Issue 1) Peer-Reviewed

  Jan. 28, 20139,488 words Article 1550LOsteoarthritis (OA) is the most common form of arthritis and has multiple risk factors including joint injury. The purpose of this study was to characterize the histologic development of OA in a mouse model where OA is...

• Vitamin K status and lower extremity function in older adults: the health aging and body composition study

  Authors:M. Kyla Shea, Richard F. Loeser, Fang-Chi Hsu, Sarah L. Booth, Michael Nevitt, Eleanor M. Simonsick, et al.From:The Journals of Gerontology, Series A (Vol. 71, Issue 10) Peer-Reviewed

  Oct. 2016290 words Author abstract, Rep...

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• Relationship of objectively-measured habitual physical activity to chronic inflammation and fatigue in middle-aged and older adults

  Authors:Barbara J. Nicklas, Daniel P. Beavers, Shannon L. Mihalko, Gary D. Miller, Richard F. Loeser, and Stephen P. MessierFrom:The Journals of Gerontology, Series A (Vol. 71, Issue 11) Peer-Reviewed

  Nov. 2016272 words Author abstract, Rep...

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• Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.

  Authors:Jeffrey N. Katz, Kaetlyn R. Arant, and Richard F. LoeserFrom:JAMA, The Journal of the American Medical Association (Vol. 325, Issue 6) Peer-Reviewed

  Feb. 9, 202136 words Report

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• Cost-effectiveness of exercise and diet in overweight and obese adults with knee osteoarthritis

  Authors:Mary A. Sevick, Gary D. Miller, Richard F. Loeser, Jeff D. Williamson, and Stephen P. MessierFrom:Medicine and Science in Sports and Exercise (Vol. 41, Issue 6) Peer-Reviewed

  June 200958 words Report

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• Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcome among overweight and obese adults with knee osteoarthritis

  Authors:Stephen P. Messier, Jeffery J. Carr, Jeff D. Williamson, Felix Eckstein, Mary F. Lyles, David J. Hunter, et al.From:JAMA, The Journal of the American Medical Association (Vol. 310, Issue 12) Peer-Reviewed

  Sept. 25, 201359 words Report

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• A Comprehensive 3-Year Internal Medicine Residency Research Curriculum

  Authors:Jimmy Ruiz, Eric L. Wallace, David P. Miller, Richard F. Loeser, Matthew Miles, Thomas D. DuBose, et al.From:American Journal of Medicine (Vol. 124, Issue 5) Peer-Reviewed

  May 2011107 words Article

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• Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-[beta]I

  Authors:Marcello DelCarlo and Richard F. LoeserFrom:American Journal of Physiology (Consolidated) (Vol. 290, Issue 3) Peer-Reviewed

  Mar. 2006200 words Author abstract 60L

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• Osteoarthritis: 20 clinical pearls; when the sources of symptoms have been pinpointed, treatment can be chosen

  Authors:Najia Shakoor and Richard F. LoeserFrom:The Journal of Musculoskeletal Medicine (Vol. 25, Issue 10) Peer-Reviewed

  Oct. 20083,479 words Disease/Disorder ove... ABSTRACT: Osteoarthritis (OA) is the leading cause of chronic disability in older adults. A multitude of factors can contribute to the disease process. Only a portion of patients who have radiographic evidence of OA...

• Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis: The START Randomized Clinical Trial.

  Authors:Stephen P. Messier, Shannon L. Mihalko, Daniel P. Beavers, Barbara J. Nicklas, Paul DeVita, J. Jeffery Carr, et al.From:JAMA, The Journal of the American Medical Association (Vol. 325, Issue 7) Peer-Reviewed

  Feb. 16, 202144 words Report

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• Osteoarthritis: 20 Clinical pearls; when the sources of symptoms have been pinpointed, treatment can be chosen. (20th Anniversary Special Series)

  Authors:Najia Shakoor and Richard F. LoeserFrom:The Journal of Musculoskeletal Medicine (Vol. 20, Issue 4) Peer-Reviewed

  Apr. 20033,440 words Article ABSTRACT: Osteoarthritis (OA) is the leading cause of chronic disability in older adults. A multitude of factors can contribute to the disease process. Only a portion of patients who have radiographic evidence of OA...

• Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study

  Authors:Stephen P. Messier, Richard F. Loeser, Michelle N. Mitchell, Gianfranco Valle, Timothy P. Morgan, W. Jack Rejeski, et al.From:Journal of the American Geriatrics Society (Vol. 48, Issue 9) Peer-Reviewed

  Sept. 200077 words Article

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• Knee joint loading in knee osteoarthritis: Influence of abdominal and thigh fat

  Authors:Stephen P. Messier, Daniel P. Beavers, Richard F. Loeser, J. Jeffery Carr, Shubham Khajanchi, Claudine Legault, et al.From:Medicine and Science in Sports and Exercise (Vol. 46, Issue 9) Peer-Reviewed

  Sept. 201476 words Article

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