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    Academic Journals

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• Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-[beta] signaling.

  Authors:Robert J. Tower, Zhu Li, Yu-Hao Cheng, Xue-Wei Wang, Labchan Rajbhandari, Qian Zhang, et al.From:Proceedings of the National Academy of Sciences of the United States (Vol. 118, Issue 42) Peer-Reviewed

  Oct. 19, 202110,246 words Report 1580L

   Abstract Only

• Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.

  Authors:Qian Zhang, Larry D. Mesner, Gina M. Calabrese, Naomi Dirckx, Zhu Li, Angela Verardo, et al.From:Journal of Clinical Investigation (Vol. 131, Issue 7) Peer-Reviewed

  Apr. 1, 20219,191 words Report 1430LBone mineral density (BMD) is a highly heritable predictor of osteoporotic fracture. GWAS have identified hundreds of loci influencing BMD, but few have been functionally analyzed. In this study, we show that SNPs within...

• In vivo targeting of activated leukocytes by a (beta.sub.2)-integrin binding peptide

  Authors:Tanja-Maria Ranta, Juho Suojanen, Oula Penate-Medina, Olga Will, Robert J. Tower, Claus Gluer, et al.From:Molecular Diagnosis & Therapy (Vol. 18, Issue 1) Peer-Reviewed

  January-February 2014 Report

   Citation Only

• The KISS1 receptor as an in vivo microenvironment imaging biomarker of multiple myeloma bone disease

  Authors:Julia Dotterweich, Robert J. Tower, Andreas Brandl, Marc Muller, Lorenz C. Hofbauer, Andreas Beilhack, et al.From:PLoS ONE (Vol. 11, Issue 5) Peer-Reviewed

  May 9, 20167,481 words Report 1600LMultiple myeloma is one of the most common hematological diseases and is characterized by an aberrant proliferation of plasma cells within the bone marrow. As a result of crosstalk between cancer cells and the bone...

• Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

  Authors:Naomi Dirckx, Robert J. Tower, Evi M. Mercken, Roman Vangoitsenhoven, Caroline Moreau-Triby, Tom Breugelmans, et al.From:Journal of Clinical Investigation (Vol. 128, Issue 3) Peer-Reviewed

  Mar. 201812,397 words Report 1600LThe skeleton has emerged as an important regulator of systemic glucose homeostasis, with osteocalcin and Insulin representing prime mediators of the interplay between bone and energy metabolism. However, genetic...

• Analysis of short-term treatment with the phosphodiesterase type 5 inhibitor tadalafil on long bone development in young rats

  Authors:Luqiang Wang, Haoruo Jia, Robert J. Tower, Michael A. Levine, and Ling QinFrom:American Journal of Physiology (Consolidated) (Vol. 315, Issue 4) Peer-Reviewed

  Oct. 2018259 words Author abstract, Rep...

   Abstract Only

• Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells.

  Authors:Jiajia Xu, Yiyun Wang, Ching-Yun Hsu, Stefano Negri, Robert J Tower, Yongxing Gao, et al.From:eLife (Vol. 9) Peer-Reviewed

  Oct. 12, 202020,169 words Article 1410LTissue resident mesenchymal stem/stromal cells (MSCs) occupy perivascular spaces. Profiling human adipose perivascular mesenchyme with antibody arrays identified 16 novel surface antigens, including endolysosomal protein...