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From:PLoS ONE (Vol. 16, Issue 3) Peer-ReviewedCCR2 is the major chemokine receptor that regulates appropriate trafficking of inflammatory monocytes, but the role of this chemokine receptor and its ligands during primary and secondary infection with intracellular...
From:PLoS ONE (Vol. 13, Issue 5) Peer-ReviewedThere are no defined correlates of protection for any intracellular pathogen, including the bacterium Francisella tularensis, which causes tularemia. Evaluating vaccine efficacy against sporadic diseases like tularemia...
From:PLoS ONE (Vol. 15, Issue 8) Peer-ReviewedProduction of IFN-[gamma] is a key innate immune mechanism that limits replication of intracellular bacteria such as Francisella tularensis (Ft) until adaptive immune responses develop. Previously, we demonstrated that...
From:Chest (Vol. 111, Issue 3) Peer-ReviewedBackground: Serologic methods for diagnosis of tuberculosis have been widely investigated owing to their low cost and rapid technical execution. Sensitivity and specificity of different tests have been reported to be...
From:PLoS ONE (Vol. 10, Issue 5) Peer-ReviewedIn the last decade several new vaccines against Francisella tularensis, which causes tularemia, have been characterized in animal models. Whereas many of these vaccine candidates showed promise, it remains critical to...
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