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    Academic Journals

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• White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation

  Authors:Charlotte E. Teunissen, Markus Otto, Sebastiaan Engelborghs, Sanna-Kaisa Herukka, Sylvain Lehmann, Piotr Lewczuk, et al.From:Alzheimer's Research & Therapy (Vol. 10, Issue 1) Peer-Reviewed

  Mar. 15, 20185,780 words Report 1570LBody fluid biomarkers have great potential for different clinical purposes, including diagnosis, prognosis, patient stratification and treatment effect monitoring. This is exemplified by current use of several excellent...

• Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for alzheimer disease

  Authors:Ronald Lautner, Sebastian Palmqvist, Niklas Mattsson, Ulf Andreasson, Anders Wallin, Erik Palsson, et al.From:JAMA Psychiatry (Vol. 71, Issue 10) Peer-Reviewed

  Oct. 2014 Report

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• Clinical use of cerebrospinal fluid biomarkers in Alzheimer's disease

  Authors:Henrik Zetterberg, Michael P. Lunn, and Sanna-Kaisa HerukkaFrom:Biomarkers in Medicine (Vol. 6, Issue 4) Peer-Reviewed

  Aug. 20123,940 words Report 1470LAuthor(s): Henrik Zetterberg [*] 1 2 , Michael P Lunn 2 3 , Sanna-Kaisa Herukka 4 5 KEYWORDS : Alzheimer's disease; amyloid; biomarkers; blood-brain barrier; cerebrospinal fluid; inflammation; tau Background...

• Preclinical effects of APOE [epsilon]4 on cerebrospinal fluid A[beta]42 concentrations

  Authors:Ronald Lautner, Philip S. Insel, Tobias Skillb?ck, Bob Olsson, Mikael Land?n, Giovanni B. Frisoni, et al.From:Alzheimer's Research & Therapy (Vol. 9, Issue 1) Peer-Reviewed

  Oct. 23, 20173,664 words Report 1600LBackground From earlier studies it is known that the APOE [epsilon]2/[epsilon]3/[epsilon]4 polymorphism modulates the concentrations of cerebrospinal fluid (CSF) beta-amyloid.sub.1-42 (A[beta]42) in patients with...

• Structural MRI in Frontotemporal Dementia: Comparisons between Hippocampal Volumetry, Tensor-Based Morphometry and Voxel-Based Morphometry

  Authors:Miguel Angel Munoz-Ruiz, Paivi Hartikainen, Juha Koikkalainen, Robin Wolz, Valtteri Julkunen, Eini Niskanen, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 20, 201210,109 words Article 1520LBackground MRI is an important clinical tool for diagnosing dementia-like diseases such as Frontemporal Dementia (FTD). However there is a need to develop more accurate and standardized MRI analysis methods....

• CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment

  Authors:Niklas Mattsson, Henrik Zetterberg, Oskar Hansson, Niels Andreasen, Lucilla Parnetti, Michael Jonsson, et al.From:JAMA, The Journal of the American Medical Association (Vol. 302, Issue 4) Peer-Reviewed

  July 22, 200943 words Clinical report

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• Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study.

  Authors:Marie Bruun, Kristian S. Frederiksen, Hanneke F.M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, et al.From:Alzheimer's Research & Therapy (Vol. 11, Issue 1) Peer-Reviewed

  Mar. 20, 20195,872 words Report 1490LBackground In clinical practice, it is often difficult to predict which patients with cognitive complaints or impairment will progress or remain stable. We assessed the impact of using a clinical decision support...

• Cerebrospinal Fluid Biomarker and Brain Biopsy Findings in Idiopathic Normal Pressure Hydrocephalus

  Authors:Okko T. Pyykko, Miikka Lumela, Jaana Rummukainen, Ossi Nerg, Toni T. Seppala, Sanna-Kaisa Herukka, et al.From:PLoS ONE (Vol. 9, Issue 3) Peer-Reviewed

  Mar. 17, 20145,354 words Article 1550LAuthor(s): Okko T. Pyykkö 1,*, Miikka Lumela 1, Jaana Rummukainen 4, Ossi Nerg 2, Toni T. Seppälä 3, Sanna-Kaisa Herukka 2,3, Anne M. Koivisto 2,3, Irina Alafuzoff 5, Lakshman Puli 3, Sakari Savolainen 1, Hilkka...

• Predicting AD Conversion: Comparison between Prodromal AD Guidelines and Computer Assisted PredictAD Tool

  Authors:Yawu Liu, Jussi Mattila, Miguel Angel Munoz Ruiz, Teemu Paajanen, Juha Koikkalainen, Mark van Gils, et al.From:PLoS ONE (Vol. 8, Issue 2) Peer-Reviewed

  Feb. 12, 20135,647 words Article 1520LPurpose To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory...

• Genetic Loci Associated with Alzheimer's Disease and Cerebrospinal Fluid Biomarkers in a Finnish Case-Control Cohort

  Authors:Lyzel S. Elias-Sonnenschein, Seppo Helisalmi, Teemu Natunen, Anette Hall, Teemu Paajanen, Sanna-Kaisa Herukka, et al.From:PLoS ONE (Vol. 8, Issue 4) Peer-Reviewed

  Apr. 3, 20135,102 words Report 1310LAuthor(s): Lyzel S. Elias-Sonnenschein 1 , Seppo Helisalmi 2 , * , Teemu Natunen 2 , Anette Hall 2 , Teemu Paajanen 2 , Sanna-Kaisa Herukka 2 , Marjo Laitinen 2 , Anne M. Remes 2 , Anne M. Koivisto 2 , Kari M. Mattila 3...

• Differential Sialylation of Serpin A1 in the Early Diagnosis of Parkinson's Disease Dementia

  Authors:Sarah Jesse, Stefan Lehnert, Olaf Jahn, Lucilla Parnetti, Hilkka Soininen, Sanna-Kaisa Herukka, et al.From:PLoS ONE (Vol. 7, Issue 11) Peer-Reviewed

  Nov. 8, 20127,168 words Article 1560LAuthor(s): Sarah Jesse 1 , Stefan Lehnert 1 , Olaf Jahn 2 , 3 , Lucilla Parnetti 4 , Hilkka Soininen 5 , Sanna-Kaisa Herukka 5 , Petra Steinacker 1 , Saskia Tawfik 1 , Hayrettin Tumani 1 , Christine A. F. von Arnim 1 ,...