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From:PLoS ONE (Vol. 9, Issue 11) Peer-ReviewedIn the era of targeted therapy, mutation profiling of cancer is a crucial aspect of making therapeutic decisions. To characterize cancer at a molecular level, the use of formalin-fixed paraffin-embedded tissue is...
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From:PLoS ONE (Vol. 7, Issue 8) Peer-ReviewedBackground Given the high incidence of metastatic esophageal squamous cell carcinoma, especially in Asia, we screened for the presence of somatic mutations using OncoMap platform with the aim of defining subsets of...
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From:Journal of Oncology (Vol. 2022) Peer-ReviewedAberrations in the fibroblast growth factor receptor2 (FGFR2) gene, including genetic alterations and chromosomal rearrangements, lead to the development and progression of cancer with poor prognosis. However, the...
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From:JAMA, The Journal of the American Medical Association (Vol. 323, Issue 13) Peer-ReviewedCitation Only
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From:Journal of Oncology (Vol. 2019) Peer-ReviewedSuccessful identification and targeting of oncogenic gene fusion is a major breakthrough in cancer treatment. Here, we investigate the therapeutic implications and feasibility of using a targeted RNA sequencing panel to...
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From:PLoS ONE (Vol. 8, Issue 3) Peer-ReviewedAuthor(s): Do-Young Park 1 , Young-Tae Ahn 1 , Se-Hoon Park 1 , Chul-Sung Huh 1 , * , Sae-Rom Yoo 3 , Rina Yu 2 , 4 , Mi-Kyung Sung 2 , 5 , Robin A. McGregor 2 , Myung-Sook Choi 2 , 3 , * Introduction The...
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From:Nature Medicine (Vol. 21, Issue 5) Peer-ReviewedGastric cancer, a leading cause of cancer-related deaths, is a heterogeneous disease. We aim to establish clinically relevant molecular subtypes that would encompass this heterogeneity and provide useful clinical...
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From:PLoS ONE (Vol. 8, Issue 12) Peer-ReviewedAuthor(s): Guhyun Kang 1,7, Woo Cheol Hwang 1,5, In-Gu Do 1, Kai Wang 2, So Young Kang 1, Jeeyun Lee 3, Se Hoon Park 3, Joon Oh Park 3, Won Ki Kang 3, Jiryeon Jang 3, Min-Gew Choi 4, Jun Ho Lee 4, Tae Sung Sohn 4, Jae...
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From:PLoS ONE (Vol. 9, Issue 3) Peer-ReviewedAuthor(s): Jeeyun Lee 1, Insuk Sohn 2, In-Gu Do 2,3, Kyoung-Mee Kim 3, Se Hoon Park 1, Joon Oh Park 1, Young Suk Park 1, Ho Yeong Lim 1, Tae Sung Sohn 4, Jae Moon Bae 4, Min Gew Choi 4, Do Hoon Lim 5, Byung Hoon Min 6,...