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From:PLoS ONE (Vol. 14, Issue 7) Peer-ReviewedBackground Two manufacturers, Maxim Biomedical and Sedia Biosciences Corporation, supply CDC-approved versions of the HIV-1 Limiting Antigen Avidity EIA (LAg) for detecting 'recent' HIV infection in cross-sectional...
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From:PLoS ONE (Vol. 16, Issue 5) Peer-ReviewedObjective To characterize the evolution of central nervous system (CNS) inflammation in HIV-1 infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to grouped subjects representing a broad...
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From:PLoS ONE (Vol. 9, Issue 2) Peer-ReviewedAuthor(s): Cecilia M. Shikuma 1,*, Dominic C. Chow 1, Louie Mar A. Gangcuangco 1, Guangxiang Zhang 1, Sheila M. Keating 2, Philip J. Norris 2,3, Todd B. Seto 1,4, Nisha Parikh 1,4, Kalpana J. Kallianpur 1, Beau K....
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From:PLoS ONE (Vol. 12, Issue 2) Peer-ReviewedBackground Assays have been developed for cross-sectional HIV incidence estimation using plasma samples. Large scale surveillance programs are planned using dried blood spot (DBS) specimens for incidence assessment....
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From:PLoS ONE (Vol. 6, Issue 6) Peer-ReviewedIntroduction Biomarker-based cross-sectional incidence estimation requires a Recent Infection Testing Algorithm (RITA) with an adequately large mean recency duration, to achieve reasonable survey counts, and a low...
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From:PLoS ONE (Vol. 14, Issue 9) Peer-ReviewedLaboratory assays for identifying recent HIV-1 infections are widely used for estimating incidence in cross-sectional population-level surveys in global HIV-1surveillance. Adequate assay and laboratory performance are...
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From:PLoS ONE (Vol. 11, Issue 2) Peer-ReviewedBackground Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV...
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From:PLoS ONE (Vol. 15, Issue 4) Peer-ReviewedPeople with sickle cell disease (SCD) are reported to have low rates of HIV infection, slower progression to AIDS and lower HIV-associated mortality compared to the general population. Mechanisms of potential resistance...
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From:Nature Medicine (Vol. 10, Issue 11) Peer-ReviewedAuthor(s): Helen McShane (corresponding author) [1]; Ansar A Pathan [1]; Clare R Sander [1]; Sheila M Keating [1]; Sarah C Gilbert [2]; Kris Huygen [3]; Helen A Fletcher [1]; Adrian V S Hill [1, 3] Protective...
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From:PLoS ONE (Vol. 5, Issue 9) Peer-ReviewedMalaria remains one of the world's greatest killers and a vaccine is urgently required. There are no established correlates of protection against malaria either for natural immunity to the disease or for immunity...