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    Academic Journals

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• N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats.

  Authors:Yitong Pan, Shuna Yu, Jianxin Wang, Wanzhen Li, Huiting Li, Chen Bai, et al.From:PeerJ (Vol. 9) Peer-Reviewed

  Aug. 10, 20218,737 words Article 1360LThe aim of this study was to investigate the changes of TLR4/NLRP3 signal during hepatic ischemia-reperfusion injury (HIRI) and to verify whether N-acetyl-L-tryptophan (L-NAT) protected hepatocytes by regulating the...

• N-acetyl-serotonin protects HepG2 cells from oxidative stress injury induced by hydrogen peroxide

  Authors:Jiying Jiang, Shuna Yu, Zhengchen Jiang, Cuihong Liang, Wenbo Yu, Jin Li, et al.From:Oxidative Medicine and Cellular Longevity (Vol. 2014) Peer-Reviewed

  Annual 20148,240 words Report 1420LOxidative stress plays an important role in the pathogenesis of liver diseases. N-Acetyl-serotonin (NAS) has been reported to protect against oxidative damage, though the mechanisms by which NAS protects hepatocytes...

• Inhibition of excessive mitophagy by N-acetyl-L-tryptophan confers hepatoprotection against Ischemia-Reperfusion injury in rats.

  Authors:Huiting Li, Yitong Pan, Hongjuan Wu, Shuna Yu, Jianxin Wang, Jie Zheng, et al.From:PeerJ (Vol. 8) Peer-Reviewed

  Apr. 9, 20206,623 words Article 1400LIn order to investigate the mechnism of hepatoprotective of N-acetyl-L-tryptophan (L-NAT) against ischemia-reperfusion (I/R) injury, the effects of L-NAT were investigated in hepatic ischemia-reperfusion injury (HIRI)...