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From:PLoS ONE (Vol. 16, Issue 3) Peer-ReviewedBackground IgA nephropathy (IgAN) advances from multiple pathogenic "hits" resulting in poorly O-galactosylated IgA1 glycoforms (Gd-IgA1), production of antibodies and glomerular deposition of immune complexes. A...
From:PLoS ONE (Vol. 5, Issue 5) Peer-ReviewedBackground IgA nephropathy (IgAN) and nephritis in Systemic Lupus Erythematosus (SLE) are two common forms of glomerulonephritis in which genetic findings are of importance for disease development. We have recently...
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