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    Academic Journals

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• Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity

  Authors:Rene Michael Hoet, Edward H Cohen, Rachel Baribault Kent, Kristin Rookey, Sonia Schoonbroodt, Shannon Hogan, et al.From:Nature Biotechnology (Vol. 23, Issue 3) Peer-Reviewed

  Mar. 20055,634 words Article Author(s): René Michael Hoet [2, 4]; Edward H Cohen [1, 4]; Rachel Baribault Kent [1]; Kristin Rookey [1]; Sonia Schoonbroodt [2]; Shannon Hogan [1]; Louise Rem [2]; Nicolas Frans [2]; Marc Daukandt [2]; Henk Pieters...

• The Breadth of Cross Sub-Type Neutralisation Activity of a Single Domain Antibody to Influenza Hemagglutinin Can Be Increased by Antibody Valency

  Authors:Simon E. Hufton, Paul Risley, Christina R. Ball, Diane Major, Othmar G. Engelhardt, and Stephen PooleFrom:PLoS ONE (Vol. 9, Issue 8) Peer-Reviewed

  Aug. 1, 201412,261 words Article 1620LThe response to the 2009 A(H1N1) influenza pandemic has highlighted the need for additional strategies for intervention which preclude the prior availability of the influenza strain. Here, 18 single domain VHH...

• Maintaining 'standards' for biosimilar monoclonal antibodies.

  Authors:Sandra Prior, Clive Metcalfe, Simon E. Hufton, Meenu Wadhwa, Christian K. Schneider, and Chris BurnsFrom:Nature Biotechnology (Vol. 39, Issue 3) Peer-Reviewed

  Mar. 20213,630 words Report 1520LAuthor(s): Sandra Prior 1 , Clive Metcalfe 1 , Simon E. Hufton 1 , Meenu Wadhwa 1 , Christian K. Schneider 1 2 , Chris Burns 1 Author Affiliations: (1) National Institute for Biological Standards and Control (NIBSC),...

• Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library

  Authors:Patrick Chames, Simon E. Hufton, Pierre G. Coulie, Barbara Uchanska-Ziegler, and Hennie R. HoogenboomFrom:Proceedings of the National Academy of Sciences of the United States (Vol. 97, Issue 14) Peer-Reviewed

  July 5, 2000193 words Article

   Abstract Only

• Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning

  Authors:Tiziano Gaiotto and Simon E. HuftonFrom:PLoS ONE (Vol. 11, Issue 10) Peer-Reviewed

  Oct. 14, 201612,764 words Article 1660LCross-neutralising monoclonal antibodies against influenza hemagglutinin (HA) are of considerable interest as both therapeutics and diagnostic tools. We have recently described five different single domain antibodies...