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• A TLR5 mono-agonist restores inhibited immune responses to Streptococcus pneumoniae during influenza virus infection in human monocytes.

  Authors:Paula T. Maguire, Sinéad T. Loughran, Ruth Harvey, and Patricia A. JohnsonFrom:PLoS ONE (Vol. 16, Issue 10) Peer-Reviewed

  Oct. 13, 20217,584 words Report 1490LInfluenza A virus (IAV) predisposes individuals to often more severe secondary bacterial infections with Streptococcus pneumonia (S. pneumoniae). The outcomes of these infections may be made worse with the increase in...

• Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-[gamma] responses to pneumococcus in vitro in human monocytes

  Authors:Sinead T. Loughran, Patrick A. Power, Paula T. Maguire, Samantha L. McQuaid, Paul J. Buchanan, Ingileif Jonsdottir, et al.From:PLoS ONE (Vol. 13, Issue 9) Peer-Reviewed

  Sept. 7, 20188,878 words Report 1610LIt is well accepted that influenza A virus predisposes individuals to often more severe superinfections with Streptococcus pneumonia. However, the mechanisms that lead to this synergy are not clearly understood. Recent...