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From:Polymer Engineering and Science (Vol. 35, Issue 10) Peer-ReviewedFountain flow for isothermal viscoelastic fluids is simulated by a numerical method based on a combination of a finite element method and a finite volume method. For the treatment of moving free surfaces, a fringe...
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From:Regenerative Medicine (Vol. 2, Issue 1)Author(s): Stephen M Richardson 1 Tissue engineering has tremendous potential for the treatment of a wide range of medical conditions. In combination with this, the developments in the fields of embryonic stem cells...
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From:PLoS ONE (Vol. 7, Issue 3) Peer-ReviewedAuthor(s): Sandra Strassburg 1 , Nigel W. Hodson 1 , Patrick I. Hill 2 , Stephen M. Richardson 1 , Judith A. Hoyland 1 , * Introduction A change in cellular phenotype of the nucleus pulposus (NP) cells residing in...
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From:PLoS ONE (Vol. 12, Issue 5) Peer-ReviewedTo improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support...
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From:Regenerative Medicine (Vol. 8, Issue 1)Author(s): Francesca E Ludwinski 1 , Kanna Gnanalingham 2 , Stephen M Richardson 1 , Judith A Hoyland [*] 3 KEYWORDS : degeneration; intervertebral disc; low back pain; notochord; nucleus pulposus; phenotype;...
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From:PLoS ONE (Vol. 11, Issue 1) Peer-ReviewedIntroduction Loss of annulus fibrosus (AF) integrity predisposes to disc herniation and is associated with IVD degeneration. Successful implementation of biomedical intervention therapy requires in-depth knowledge of...
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From:PLoS ONE (Vol. 12, Issue 11) Peer-ReviewedAuthor(s): Christopher A. Smith, Tim N. Board, Paul Rooney, Mark J. Eagle, Stephen M. Richardson, Judith A. Hoyland In the Funding section, the grant numbers are missing. The grant number for the John Charnley Trust...
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From:Regenerative Medicine (Vol. 5, Issue 5)Author(s): Sandra Strassburg 1 , Stephen M Richardson 1 , Anthony J Freemont 1 , Judith A Hoyland [[dagger]] 2 KEYWORDS: co-culture; intervertebral disc regeneration; mesenchymal stem cells; nucleus pulposus...
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From:PLoS ONE (Vol. 7, Issue 10) Peer-ReviewedAuthor(s): Stephen M. Richardson, Devina Purmessur, Pauline Baird, Ben Probyn, Anthony J. Freemont, Judith A. Hoyland * Introduction Low back pain (LBP) is a widespread and debilitating disorder which causes a...
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From:Stem Cells International (Vol. 2017) Peer-ReviewedBone marrow-derived mesenchymal stem cells (MSCs) and adipose-derived multipotent/mesenchymal stem cells (ASCs) have been proposed as the ideal cell types for a range of musculoskeletal tissue engineering and...