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From:Proceedings of the National Academy of Sciences of the United States (Vol. 103, Issue 43) Peer-ReviewedAbstract Only
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From:PLoS ONE (Vol. 6, Issue 9) Peer-ReviewedAebp2 is a potential targeting protein for the mammalian Polycomb Repression Complex 2 (PRC2). We generated a mutant mouse line disrupting the transcription of Aebp2 to investigate its in vivo roles. Aebp2-mutant...
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From:PLoS ONE (Vol. 12, Issue 2) Peer-ReviewedBackground The generation of induced pluripotent stem cell (iPSC), a substitute for embryonic stem cell (ESC), requires the proper orchestration of a transcription program at the chromatin level. Our recent approach...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): Suresh Cuddapah 1 , * , Tae-Young Roh 2 , Kairong Cui 2 , Cynthia C. Jose 1 , Margaret T. Fuller 4 , Keji Zhao 2 , Xin Chen 3 , * Introduction Polycomb group (PcG) proteins, together with the...
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From:PLoS ONE (Vol. 9, Issue 1) Peer-ReviewedAuthor(s): Yoo-Wook Kwon 1,2, Yeon-Ju Chung 1,2, Joonoh Kim 1,2, Ho-Jae Lee 1,2, Jihwan Park 3, Tae-Young Roh 3, Hyun-Jai Cho 1,2,5, Chang-Hwan Yoon 4, Bon-Kwon Koo 5, Hyo-Soo Kim 1,2,5,6,* Introduction...
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From:PLoS ONE (Vol. 9, Issue 12) Peer-ReviewedVarious mammalian cells, including cancer cells, shed extracellular vesicles (EVs), also known as exosomes and microvesicles, into surrounding tissues. These EVs play roles in tumor growth and metastasis by promoting...
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From:Nature Biotechnology (Vol. 22, Issue 8) Peer-ReviewedAuthor(s): Tae-young Roh [1]; Wing Chi Ngau [2]; Kairong Cui [1]; David Landsman [2]; Keji Zhao (corresponding author) [1] The expression patterns of eukaryotic genomes are controlled by their chromatin structure,...
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From:Epigenomics (Vol. 3, Issue 1) Peer-ReviewedAuthor(s): Chang Pyo Hong 1 , Jihwan Park 1 , Tae-Young Roh [[dagger]] 2 KEYWORDS : cell reprogramming; DNA methylation; embryonic stem cell; epigenetic regulation; epigenome sequencing; histone modification;...
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From:Epigenomics (Vol. 7, Issue 1) Peer-ReviewedAuthor(s): Abdul Aziz Khan aff1 , Andrew Jeoungun Lee aff1 , Tae-Young Roh [*] aff1 aff2 Keywords: cell differentiation; development; homeobox genes; PcG recruitment; Polycomb group proteins Generally, all...