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From:Nature Medicine (Vol. 19, Issue 12) Peer-ReviewedThe above manuscript was authored by scientists from the GlaxoSmithKline (GSK) Research and Development Center in Shanghai, China, and a researcher from Baylor Medical College who later became a GSK employee. Following...
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From:Nature Medicine (Vol. 16, Issue 2) Peer-ReviewedVariation in the IL-7 receptor is associated with susceptibility to multiple sclerosis. Jingwu Zhang and his colleagues provide an explanation. They show that the cytokine IL-7 regulates the surival and proliferation of...
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From:Nature Medicine (Vol. 19, Issue 3) Peer-ReviewedRegulatory T ([T.sub.reg]) cells suppress autoimmune disease, and impaired [T.sub.reg] cell function is associated with rheumatoid arthritis. Here we demonstrate that forkhead box P3 (FOXP3) transcriptional activity...
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From:Nature Medicine (Vol. 16, Issue 2) Peer-ReviewedInterleukin-7 receptor (IL-7R) is genetically associated with susceptibility to multiple sclerosis. Here we describe that IL-7 is essential for survival and expansion of pathogenic T helper type 17 ([T.sub.H]17) cells...