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    Academic Journals

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• Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

  Authors:Frank J. Gonzalez, Radek C. Skoda, Shioko Kimura, Morio Umeno, Ulrich M. Zanger, Daniel W. Nebert, et al.From:Nature (Vol. 331, Issue 6155) Peer-Reviewed

  Feb. 4, 1988 Article

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001230 words Article

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• ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression

  Authors:Tarek Magdy, Rudolf Arlanov, Stefan Winter, Thomas Lang, Kathrin Klein, Yu Toyoda, et al.From:Pharmacogenomics (Vol. 14, Issue 12) Peer-Reviewed

  Sept. 20138,588 words Report 1470LAuthor(s): Tarek Magdy 1 , Rudolf Arlanov 1 , Stefan Winter 1 , Thomas Lang 1 , Kathrin Klein 1 , Yu Toyoda 2 , Toshihisa Ishikawa 3 , Matthias Schwab 1 4 , Ulrich M Zanger [*] 5 KEYWORDS : 5-fluorouracil;...

• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001 Brief article

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• Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms of efavirenz pharmacokinetics and treatment response: an AIDS clinical trials group study

  Authors:Heather J. Ribaudo, Huan Liu, Matthias Schwab, Elke Schaeffeler, Michel Eichelbaum, Alison A. Motsinger-Reit, et al.From:Journal of Infectious Diseases (Vol. 202, Issue 5) Peer-Reviewed

  Sept. 1, 2010 Clinical report

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• Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease

  Authors:Yijing Zhang, Kathrin Klein, Aarathi Sugathan, Najlla Nassery, Alan Dombkowski, Ulrich M. Zanger, et al.From:PLoS ONE (Vol. 6, Issue 8) Peer-Reviewed

  Aug. 12, 201111,088 words Article 1660LSex-differences in human liver gene expression were characterized on a genome-wide scale using a large liver sample collection, allowing for detection of small expression differences with high statistical power. 1,249...

• Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus

  Authors:Landry K. Kamdem, Frank Streit, Ulrich M. Zanger, Jurgen Brockmoller, Michael Oellerich, Victor W. Armstrong, et al.From:Clinical Chemistry (Vol. 51, Issue 8) Peer-Reviewed

  Aug. 20055,233 words Article 1320L

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• Frequency of C3435T polymorphism of MDR1 gene in African people

  Authors:Elke Schaeffeler, Michel Eichelbaum, Ulrich Brinkmann, Anja Penger, Steven Asante-Poku, Ulrich M. Zanger, et al.From:The Lancet (Vol. 358, Issue 9279) Peer-Reviewed

  Aug. 4, 2001197 words Article

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• High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC

  Authors:Elke Schaeffeler, Thomas Lang, Ulrich M. Zanger, Michel Eichelbaum, and Matthias SchwabFrom:Clinical Chemistry (Vol. 47, Issue 3) Peer-Reviewed

  Mar. 20014,824 words Article 1480L

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• Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro

  Authors:Zeruesenay Desta, Tanja Saussele, Bryan Ward, Julia Blievernicht, Lang Li, Kathrin Klein, et al.From:Pharmacogenomics (Vol. 8, Issue 6) Peer-Reviewed

  June 20076,894 words Report Author(s): Zeruesenay Desta [[dagger]] 1 , Tanja Saussele 2 , Bryan Ward 1 , Julia Blievernicht 2 , Lang Li 1 , Kathrin Klein 2 , David A Flockhart 1 , Ulrich M Zanger [[dagger]] 2 Keywords: AIDS; bupropion;...

• Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance

  Authors:Ulrich M Zanger, Kathrin Klein, Tanja Saussele, Julia Blievernicht, Marco H Hofmann, and Matthias SchwabFrom:Pharmacogenomics (Vol. 8, Issue 7) Peer-Reviewed

  July 200711,043 words Clinical report Author(s): Ulrich M Zanger [[dagger]] 1 2 , Kathrin Klein 1 2 , Tanja Saussele 1 2 , Julia Blievernicht 1 2 , Marco H Hofmann 1 2 , Matthias Schwab 1 2 Keywords: AIDS; bupropion; cyclophosphamide; cytochrome P450;...

• Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes

  Authors:Markus Schirmer, Albert Rosenberger, Kathrin Klein, Bettina Kulle, Mohammad R Toliat, Peter Nurnberg, et al.From:Pharmacogenomics (Vol. 8, Issue 5) Peer-Reviewed

  May 20075,928 words Clinical report Author(s): Markus Schirmer 1 , Albert Rosenberger 2 , Kathrin Klein 3 , Bettina Kulle 4 , Mohammad R Toliat 5 , Peter Nürnberg 5 , Ulrich M Zanger 3 , Leszek Wojnowski [[dagger]] 6 Keywords: CYP3A4; drug...

• LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods

  Authors:Ronny Feuer, Sebastian Vlaic, Janine Arlt, Oliver Sawodny, Uta Dahmen, Ulrich M. Zanger, et al.From:PLoS ONE (Vol. 10, Issue 9) Peer-Reviewed

  Sept. 1, 20158,364 words Report 1420LBackground Gene expression analysis is an essential part of biological and medical investigations. Quantitative real-time PCR (qPCR) is characterized with excellent sensitivity, dynamic range, reproducibility and is...

• Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained

  Authors:Goran Kungulovski, Suneetha Nunna, Maria Thomas, Ulrich M Zanger, Richard Reinhardt, and Albert JeltschFrom:Epigenetics & Chromatin (Vol. 8, Issue 1) Peer-Reviewed

  Mar. 18, 20156,594 words Article 1470LBackground DNA methylation and histone 3 lysine 9 (H3K9) methylation are considered as epigenetic marks that can be inherited through cell divisions. To explore the functional consequences and stability of these...

• Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia

  Authors:Martin Stanulla, Thomas Flohr, Elke Schaeffeler, Gunnar Cario, Wof-Dieter Ludwig, Andre Schrauder, et al.From:JAMA, The Journal of the American Medical Association (Vol. 293, Issue 12) Peer-Reviewed

  Mar. 23, 200554 words Article

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• MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms

  Authors:Julia K. Blievernicht, Elke Schaeffeler, Kathrin Klein, Michel Eichelbaum, Matthias Schwab, and Ulrich M. ZangerFrom:Clinical Chemistry (Vol. 53, Issue 1) Peer-Reviewed

  Jan. 20075,231 words Article 1490L

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