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From:PLoS ONE (Vol. 8, Issue 12) Peer-ReviewedPertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4.sup.+ T cells are essential for protective immunity against pertussis. For better understanding of the...
From:PLoS ONE (Vol. 11, Issue 10) Peer-ReviewedEffective immunity against Bordetella pertussis is currently under discussion following the stacking evidence of pertussis resurgence in the vaccinated population. Natural immunity is more effective than vaccine-induced...
From:PLoS ONE (Vol. 11, Issue 2) Peer-ReviewedPertussis, caused by infection with the gram negative B. pertussis bacterium, is a serious respiratory illness that can last for months. While B. pertussis infection rates are estimated between 1-10% in the general...
From:PLoS ONE (Vol. 11, Issue 8) Peer-ReviewedThe potency of whole-cell pertussis (wP) vaccines is still determined by an intracerebral mouse protection test. To allow development of suitable in vitro alternatives to this test, insight into relevant parameters to...
From:PLoS ONE (Vol. 9, Issue 8) Peer-ReviewedWorldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies. Since natural infections induce a longer-lasting immunity than vaccinations, detailed knowledge...
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