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From:PLoS ONE (Vol. 12, Issue 1) Peer-ReviewedObjective We conducted this meta-analysis of randomized controlled trials (RCTs) to investigate whether remote ischemic conditioning (RIC) could improve graft functions in kidney transplantation. Methods...
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From:PLoS ONE (Vol. 9, Issue 4) Peer-ReviewedBackground: Transforming growth factor-beta l(TGF-[beta]1) is involved in the development of acute rejection (AR) episodes in solid organ transplant recipients; and a number of studies have been conducted to investigate...
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From:PLoS ONE (Vol. 6, Issue 7) Peer-ReviewedBackground K.sub.V 7/KCNQ channels are widely expressed in neurons and they have multiple important functions, including control of excitability, spike afterpotentials, adaptation, and theta resonance. Mutations in...
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From:PLoS ONE (Vol. 7, Issue 11) Peer-ReviewedAuthor(s): Xiao-Fei Gao, Jin-Jing Yao, Yan-Lin He, Changlong Hu * , Yan-Ai Mei * Introduction The sigma receptor was originally described as a novel opioid receptor subtype, but it is now considered to be a unique...
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From:PLoS ONE (Vol. 7, Issue 7) Peer-ReviewedCyproheptadine (CPH) is a histamine- and serotonin-receptor antagonist, and its effects are observed recently in the modulation of multiple intracellular signals. In this study, we used cortical neurons and HEK-293...