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From:Expert Review of Cardiovascular Therapy (Vol. 7, Issue 3) Peer-ReviewedAuthor(s): Yoonjung Park 1 , Junxi Wu 2 , Hanrui Zhang 3 , Yong Wang 4 , Cuihua Zhang [[dagger]] 5 Vascular dysfunction associated with Type 2 diabetes is initially manifested in the prediabetic condition and...
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From:International Journal of Vascular Medicine (Vol. 2017) Peer-ReviewedThe objective of this meta-analysis is to summarize the effect of exercise intervention on flow-mediated dilatation (FMD) in overweight and obese adults. We searched four electronic databases (PubMed/Medline, Scopus,...
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From:Diabetology & Metabolic Syndrome (Vol. 10, Issue 1) Peer-ReviewedBackground Vascular endothelial dysfunction induced by hyperglycemia and elevated insulin resistance is a potent risk factor for cardiovascular disease and likely contributes to multiple chronic disease complications...
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From:PLoS ONE (Vol. 12, Issue 11) Peer-ReviewedObjectives Inflammatory cytokines, such as tumor necrosis factor-[alpha] (TNF-[alpha]) and interleukin-6 (IL-6), are individually considered as important contributors to endothelial dysfunction in obesity and type 2...
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From:International Journal of Vascular Medicine (Vol. 2017) Peer-ReviewedEndoplasmic reticulum (ER) stress, which is highly associated with cardiovascular disease, is triggered by a disturbance in ER function because of protein misfolding or an increase in protein secretion. Prolonged...