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    Academic Journals

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• Deciphering regulatory protein activity in human pancreatic islets via reverse engineering of single-cell sequencing data.

  Author:Yumi ImaiFrom:Journal of Clinical Investigation (Vol. 131, Issue 24) Peer-Reviewed

  Dec. 15, 20212,345 words Report 1490LThe loss of functional [beta] cell mass contributes to development and progression of type 2 diabetes (T2D). However, the molecular mechanisms differentiating islet dysfunction in T2D from nondiabetic states remain...

• Insulin resistance or insulin deficiency: which is the primary cause of NIDDM?

  Authors:Simeon I. Taylor, Domenico Accili, and Yumi ImaiFrom:Diabetes (Vol. 43, Issue 6) Peer-Reviewed

  June 19944,889 words Article Perspectives in Diabetes Which Is the Primary Cause of NIDDM? Extensive investigations of the pathophysiology of non-insulin-dependent diabetes mellitus (NIDDM) have identified two defects in endocrine function:...

• Emergence of drug-resistant cytomegalovirus retinitis in the contralateral eyes of patients with AIDS treated with ganciclovir

  Authors:Yumi Imai, Carol Shum, Daniel F. Martin, Baruch D. Kuppermann, W. Lawrence Drew, and Todd P. MargolisFrom:Journal of Infectious Diseases (Vol. 189, Issue 4) Peer-Reviewed

  Feb. 15, 2004 Article

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• High Prevalence of Herpes Simplex Virus Type 2 in Acute Retinal Necrosis Syndrome Associated With Herpes Simplex Virus in Japan

  Authors:Norihiko Itoh, Nozomi Matsumura, Akiko Ogi, Tadayuki Nishide, Yumi Imai, Hikaru Kanai, et al.From:American Journal of Ophthalmology (Vol. 129, Issue 3) Peer-Reviewed

  Mar. 2000 Article

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• LAT Region Factors Mediating Differential Neuronal Tropism of HSV-1 and HSV-2 Do Not Act in Trans

  Authors:Andrea S. Bertke, Kathleen Apakupakul, AyeAye Ma, Yumi Imai, Anne M. Gussow, Kening Wang, et al.From:PLoS ONE (Vol. 7, Issue 12) Peer-Reviewed

  Dec. 31, 20125,943 words Article 1700LAfter HSV infection, some trigeminal ganglion neurons support productive cycle gene expression, while in other neurons the virus establishes a latent infection. We previously demonstrated that HSV-1 and HSV-2...

• Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in Obesity-prone mice

  Authors:Hiralben R. Patel, Yong Qi, Evan J. Hawkins, Stanley M. Hileman, Joel K. Elmquist, Yumi Imai, et al.From:Diabetes (Vol. 55, Issue 11) Peer-Reviewed

  Nov. 20064,243 words Article 1450LNeuropeptide Y (NPY) stimulates feeding and weight gain, but deletion of the NPY gene does not affect food intake and body weight in mice bred on a mixed genetic background. We reasoned that the orexigenic action of NPY...

• My journey from Japan to becoming a physician-scientist in the United States.

  Author:Yumi ImaiFrom:Journal of Clinical Investigation (Vol. 131, Issue 9) Peer-Reviewed

  May 1, 20211,902 words Personal account 1360L"Welcome, Yumi. Please call me Marian, not Dr. Young. We use first names here." Thus my first day in the US as a research fellow at the National Institutes of Health (NIH) started with a greeting remarkably different...

• Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion

  Authors:Michelle B. Trevino, Yui Machida, Daniel R. Hallinger, Eden Garcia, Aaron Christensen, Sucharita Dutta, et al.From:Diabetes (Vol. 64, Issue 4) Peer-Reviewed

  Apr. 2015 Report

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• Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice

  Authors:Regan Roat, Vandana Rao, Nicolai M. Doliba, Franz M. Matschinsky, John W. Tobias, Eden Garcia, et al.From:PLoS ONE (Vol. 9, Issue 2) Peer-Reviewed

  Feb. 5, 20146,413 words Article 1560LAuthor(s): Regan Roat 1, Vandana Rao 1, Nicolai M. Doliba 2, Franz M. Matschinsky 2, John W. Tobias 3, Eden Garcia 4, Rexford S. Ahima 1, Yumi Imai 1,4,* Introduction Insulin resistance commonly seen in obesity is...

• Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human [beta]-Cells and Critical for the Maintenance of Syntaxin 1a Levels in [beta]-Cells.

  Authors:Siming Liu, Joseph A. Promes, Mikako Harata, Akansha Mishra, Samuel B. Stephens, Eric B. Taylor, et al.From:Diabetes (Vol. 69, Issue 6) Peer-Reviewed

  June 2020 Report

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