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• Camostat mesilate inhibits pro-inflammatory cytokine secretion and improves cell viability by regulating MFGE8 and HMGN1 in lipopolysaccharide-stimulated DF-1 chicken embryo fibroblasts.

  Authors:Lin Yuan, Mengjie Li, Zhishuai Zhang, Wanli Li, Wei Jin, and Mingfa WangFrom:PeerJ (Vol. 9) Peer-Reviewed

  Aug. 26, 20215,565 words Article 1510LCamostat mesilate (CM) possesses potential anti-viral and anti-inflammatory activities. However, it remains unknown whether CM is involved in lipopolysaccharide (LPS)-mediated inflammatory responses and cell injury. In...

• Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment

  Authors:Wanfu Xu, Jiabi Qian, Fangyin Zeng, Songyu Li, Wenjing Guo, Liping Chen, et al.From:Journal of Experimental & Clinical Cancer Research (Vol. 38, Issue 1) Peer-Reviewed

  Mar. 6, 20196,492 words Article 1630LBackground Mast cells are being increasingly recognized as critical components in the tumor microenvironment. Protein Kinase D (PKD) is essential for the progression of prostate cancer, but its role in prostate...