Byline: Sunil. Narayan, Nandigam. Kaveer
Untreated Wilson&#x2032;s disease in advanced stage is associated with high neurological morbidity, and effective treatment with chelating agents and zinc salts has shown to prevent the development of or reverse neurological symptoms. However an overzealous treatment with zinc over a prolonged period can have its own dangers.
A 13-year-old boy presented with symptoms of difficulty in using hands, difficulty ambulating, and slurred speech for six months duration. He was diagnosed to have Wilson&#x2032;s disease at the age of nine years based on the presence of Corneal KF ring and serum ceruloplasmin value of 27.5 &#x00B5;g/dl (Normal range: 20-50 µg/dl). His CT brain had then showed bilateral caudate nucleus atrophy and normal cerebral hemispheres. He was then started on treatment with penicillamine 750 mg/day and Zinc Sulphate Monohydrate 280mg/day. His mother reported good compliance with the prescribed medication for the...
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