Perilipin polymorphisms and children obesity: variation of metabolic status and weight-loss after 5 months intervention

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Authors: Deram S., C. Nicolau, M. Rodrigues, E. Frazzatto, I. Guazzelli and A. Halpern
Date: May 2008
From: International Journal of Obesity(Vol. 32, Issue S1-2)
Publisher: Nature Publishing Group
Document Type: Brief article; Clinical report
Length: 354 words

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Perilipin is a major protein found in adipocytes and one of the key regulators of lipolysis. We examined the association in brazilian obese children (OC) of several polymorphisms at the perilipin (PLIN) locus with anthropometric, metabolic measures and weight reduction in response to a five months multi-disciplinary treatment without medication. A total of 234 OC (age 10.7 [+ or -] 1.3 years) (BMI 30.4 [+ or -] 4.4 kg/[m.sup.2]>; BMI-Zscore 2.31 [+ or -] 0.4) were evaluated at baseline and after intervention.

PLINI: 6209T>C, PLIN4:ll482G>A, PLIN5: 13041A>G, and...

Source Citation

Source Citation
Deram S., et al. "Perilipin polymorphisms and children obesity: variation of metabolic status and weight-loss after 5 months intervention." International Journal of Obesity, vol. 32, no. S1-2, 2008, p. S21. Accessed 20 Oct. 2020.
  

Gale Document Number: GALE|A190151167