Four CD-ROMs offering detailed home and family medical advice are reviewed. The American Medical Assn's Family Medical Guide acts as a 'virtual physician' guiding the user through diagnosis of symptoms and advice on treatment, offering a set of diagnostic trees laid out in a flowchart format. There is an extensive drug glossary, but no cross-links to potentially hazardous drug interactions. The Learning Co's Home Medical Adviser has thorough options for keeping records of family medical histories, has an extensive drug library listing more than 8,000 medicines, and warns of potential allergic reactions and dangerous interactions when medications are combined. Mindscape's Physicians Home Assistant has a limited interface but excellent functionality. IVI Publishing's Ultimate Medical Guide bundles Mayo Clinic Family Health and Family Pharmacist, superb medical and drug encyclopedias respectively.