Background and Design: To compare the oral ulcerations and other clinical features seen in recurrent aphthous stomatitis (RAS) and Behcet's disease (BD). Material and Method: Thirty RAS patients (20 female, 10 male), aged 20-54 years and 49 Behcet patients (32 female, 17 male), aged 19-47 years, were included in the study. Diagnosis of RAS was made in the patients who have oral ulcerations more than 3 times per year, and who does not suffer from diseases, which may cause aphthous or aphthous-like lesions. The diagnosis of BD was established according to the criteria of the International Study Group for BD. Both groups were examined for family history, age at onset, disease duration, frequency and duration of oral aphtae; additionally, during dermatological examination, dimension, localization and number of oral aphthae were recorded. Student's t-test and Mann-Whitney U tests were used for statistical analysis. Results: The mean age at onset of the disease was lower in Behcet patients than in RAS patients, and this difference was statistically significant. Conclusion: Although BD is usually considered as the initial diagnosis in cases of recurrent oral ulcerations starting at young ages and in presence of multiple oral ulcerations, and RAS is the more probable diagnosis in patients with ulcerations on the labial mucosa, further studies in a larger population are needed on this topic. (Turkderm 2010; 44: 150-2) Key Words: Recurrent aphthous stomatitis, Behcet's disease Amac: Rekurren aftoz stomatit (RAS) ve Behcet hastaliginda (BH'de) gorulen oral ulserlerin ve diger klinik ozelliklerin karsilastirilmasi Gerec ve Yontem: Calismaya RAS tanisi ile izlenen, 20-54 yas araliginda, 20'si kadin, 10'u erkek toplam 30 RAS hastasi; BH tanisi ile izlenen, 19-47 yas araliginda, 32'si kadin, 17'si erkek toplam 49 Behcet hastasi alindi. RAS tanisi; yilda uc kereden fazla oral ulser yakinmasi olan, aft veya aft benzeri lezyonlara yol acan diger klinik durumlardan ayrimi yapilmis hastalari kapsadi. BH tanisi Uluslararasi Calisma Grubu Tani Kriterlerine gore konuldu. Her iki hasta grubu aile hikayesi, hastalik baslangic yasi, hastalik suresi, oral aft sikligi ve suresi yonunden sorgulandi; dermatolojik muayenede gorulen oral aft boyutu, lokalizasyonu, sayisi kaydedildi. istatistiksel degerlendirmelerde Student's t testi ve Mann Whitney U testi kullanildi. Bulgular: Behcet hastalarinin hastalik baslangic yasinin RAS hastalarina kiyasla daha genc oldugu saptandi ve bu fark istatistiksel olarak anlamli bulundu. Sonuc: Tekrarlayan oral ulser sikayeti genc yasta baslayan ve cok sayida oral ulseri olan hastalarda oncelikli olarak BH, labial mukoza yerlesimli ulseri olan hastalarda ise oncelikli olarak RAS ontanisi akla gelmesi gerektigi dusunulse de bu konuda daha genis hasta serilerinde calismalar yapilmasina ihtiyac vardir. (Turkderm 2010; 44: 150-2) Anahtar Kelimeler: Rekurren aftoz stomatit, Behcet hastaligi
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