Sarcoidosis presenting with inguinal lympadenopathy and treated with a combination of corticosteroids and aazothioprine / Inguinal Lenfadenopati ile Seyreden ve Kortikosteroid ve Azotoprin Kombinasyonu ile tedavi edilen sarkoidoz

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Author: Metin Isik
Date: Sept. 2012
From: Turkish Journal of Rheumatology(Vol. 27, Issue 3)
Publisher: Turkish League Against Rheumatism
Document Type: Letter to the editor
Length: 682 words

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Sarcoidosis is a systemic inflammatory disorder characterized by noncaseating granulomas which mostly affect the lungs, intrathoracic lymph nodes, eyes, and skin. The defining histopathology is the presence of compact, epithelioid granulomas associated with mononuclear cell infiltration. (1) Sarcoidosis may present as an asymptomatic disease, or it may cause respiratory insufficiency, blindness, severe neurological disease, or sometimes cardiac death. (2), (3) The involvement of inguinal lymph nodes in sarcoidosis is very rare and has been reported only in a few cases before.

A 50-year-old female diabetic patient applied to our outpatient unit complaining of inguinal pain and a mass which had lasted for three months. She did not report fever, weight loss, or a history of tuberculosis but complained of sweating and pain. The ultrasonographic evaluation of the inguinal region revealed bilaterally enlarged lymph nodes of nearly 25 millimeters in diameter. A pathological evaluation of the biopsy taken from the inguinal lymph nodes showed noncaseating necrotizing granulomas which were positive for CD3 and CD20, but negative for CD30, periodic acid-Schiff (PAS),...

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Source Citation
Isik, Metin. "Sarcoidosis presenting with inguinal lympadenopathy and treated with a combination of corticosteroids and aazothioprine / Inguinal Lenfadenopati ile Seyreden ve Kortikosteroid ve Azotoprin Kombinasyonu ile tedavi edilen sarkoidoz." Turkish Journal of Rheumatology, vol. 27, no. 3, 2012, p. 212+. Accessed 4 Dec. 2020.
  

Gale Document Number: GALE|A306516629