Extraordinary pancreatic masses/Siradisi pankreas kitleleri

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Authors: Kenan Buyukasik, Ahmet Burak Toros, Aziz Ari, Hasan Bektas, Yesim Karagoz and Esra Pasaoglu
Date: June 2014
From: Istanbul Medical Journal(Vol. 15, Issue 2)
Publisher: AVES
Document Type: Article
Length: 2,106 words

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Abstract :

Objective: In this study, in light of current literature; we studied the diagnostictherapeutic and prognostic features of pancreatic lesions located in the body and tail, for which we performed distal pancreatectomy. Methods: Ten patients with pancreatic lesions, who were treated surgically with distal pancreatectomy between the years 2005-2010, in the General Surgery Clinics of Istanbul Education and Research Hospital, were analyzed retrospectively, regarding their demographic-clinical-pathological features and diagnostic methods. Results: Three of the patients were male and 7 were female. The median age of patients was 57.2 (the youngest 27, the oldest 81), with 3 of them having lesions located in the tail and 7 in the body of the pancreas. All of the patients underwent distal pancreatectomy, 5 of which had additional splenectomy. Their pathologic examinations revealed 3 serous cystad-enomas, 2 mucinous cystic neoplasms, 2 solid pseudopapillary tumors, 1 ductal adenocarcinoma, 1 acinary cell carcinoma, and 1 neuroendocrine tumor. The median follow-up interval was 2 years. Conclusion: Tumors of the pancreatic tail and body are extraordinary lesions, with low malignant potential. Most of the patients are young females. The most common complaint is abdominal pain or a palpable abdominal mass, with 50% being asymptomatic. These lesions are prone to local invasion. Prognosis is excellent, following a complete surgical resection, and recurrence is uncommon. Diagnosis and treatment of pancreatic cancer are still a major concern, due to its poor prognosis. Because there are no specific early findings, symptoms appear only when it compresses or invades the neighboring structures. Curative resection is possible in 10%-20% and 15% of pancreatic masses located in the body and tail, respectively. Early diagnosis of these lesions is still a challenge that we must overcome. Key Words: Extraordinary pancreatic mass, distal pancreatectomy Amac: Bu calismada, pankreasin govde ve distalinde yerlesim gosteren ve distal pankreatektomi uyguladigimiz siradisi pankreas lezyonlari; tani-tedavi ve prognoz acisindan guncel literatur bilgileri esliginde incelendi. Yontemler: 2005-2010 yillari arasinda Istanbul Egitim ve Arastirma Hastanesi'nde distal pankreatektomi uyguladigimiz 10 olgu, retrospektif olarak incelendi. Hastalarin demografik, klinik, patolojik ozellikleri ve tani yontemleri degerlendirildi. Bulgular: Hastalarin 3'u erkek 7'si kadindi. Yas ortalamasi 57,2 (en kucuk 27-en buyuk 81) idi. Olgularin 3'unde lezyon (%30) pankreas govdesinde, 7'sinde (%70) kuyruk yerlesimliydi. Tum hastalara distal pankreatektomi uygulandi. 5 hastaya, splenektomi de eklendi. Olgular patolojik acidan degerlendirildiginde; 3 olguda seroz kistadenom, 2 olguda solid psodo-papiller tumor, 2 olguda musinoz kistik neoplazm, 1 olguda duktal ade-nokarsinom, 1 olguda asiner hucreli karsinom, 1 olguda ise noroendokrin tumor tesbit edildi. Hastalar, ortalama 2 yil sureyle takip edildiler. Sonuc: Pankreasin govde ve kuyruk yerlesimli siradisi lezyonlari; dusuk derecede malignite potansiyeli tasiyan ve nadir gorulen lezyonlardir. Hastalarin cogu genc kadinlardir. %50 hasta asemptomatik olup, en sik karinda kitle ya da karin agrisi sikayeti ile basvururlar. Bu lezyonlar, daha cok lokal invazyon yapma egilimindedirler. Tam rezeksiyon sonrasi prognoz mukemmeldir ve rekurrens cok nadir gorulur. Pankreas kanseri ise, kotu prognozu ile tani ve tedavideki onemini korumaktadir. Pankreas kanserine ozgu erken donem bulgulari yoktur. Genellikle cevre dokulara basi ya da invazyon yapinca semptomlar ortaya cikar. Pankreas basi kanserlerinin %10-20'sine, govde ve kuyruktaki tumorlerin ise ancak %15'ine kuratif rezeksiyon yapilabilmektedir. Bu lezyonlarin erkenden ve dogru sekilde taninmasi, asilmasi gereken bir sorun olarak durmaktadir. Anahtar Kelimeler: Siradisi pankreas kitleleri, distal pankreatektomi

Source Citation

Source Citation
Buyukasik, Kenan, et al. "Extraordinary pancreatic masses/Siradisi pankreas kitleleri." Istanbul Medical Journal, vol. 15, no. 2, 2014, p. 110+. Accessed 30 Oct. 2020.
  

Gale Document Number: GALE|A378369287