The effects of hydro-alcoholic extract of celery on lipid profile of rats fed a high fat diet

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Authors: Wesam Kooti, Maryam Ghasemiboroon, Majid Asadi-Samani, Akaram Ahangarpoor, Mosayeb Noori Ahmad Abadi and Reza Afrisham
Date: June 20, 2014
From: Advances in Environmental Biology
Publisher: American-Eurasian Network for Scientific Information
Document Type: Report
Length: 3,455 words
Abstract :

Background and Objectives: Decrease in serum lipids by dietary or pharmacological intervention prevents progression of atherosclerosis and cardiovascular diseases. The aim of this study was to investigate the effects of hydro-alcoholic extract of celery (Apium graveolens) on lipid profile of rats fed a high fat diet. Materials and Methods: In this experimental study, 24 Wistar rats were randomly allocated into four groups. The control group received saline with high-fat diet and treatment groups did hydroalcoholic extract at doses of 100 and 200 mg/kg/BW with high fat diet by gavage over a 30-day period. Afterwards, the serum levels of lipids (triglyceride, cholesterol, LDL, HDL, and VLDL) were determined. The data were analyzed by one-way ANOVA test using SPSS15 software. Results: Hydro-alcoholic extract of celery significantly decreased cholesterol and LDL in treatment groups compared with control group (P 0.05). Conclusions: Probably celery consumption due to the antioxidant properties leads to appropriate changes in serum lipid profiles and reduces them. Therefore it could be useful in the treatment of hyperlipidemia. Keywords: Apium graveolens, Cholesterol, Lipid, Rat

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Source Citation   (MLA 8th Edition)
Kooti, Wesam, et al. "The effects of hydro-alcoholic extract of celery on lipid profile of rats fed a high fat diet." Advances in Environmental Biology, 2014, p. 325+. Gale Academic Onefile, Accessed 17 Sept. 2019.

Gale Document Number: GALE|A392176383