Giant liver hemangioma in patient with ileal gastrointestinal stromal tumor/Veliki hemangiom jetre kod pacijenta sa gastrointestinalnim stromalnim tumorom ileuma

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Authors: Vasilije Antic, Marjan Micev, Danijela Baskic and Violeta Mladenovic
Date: January-February 2014
From: Medicinski Pregled(Vol. 67, Issue 1-2)
Publisher: Drustvo Lekara Vojvodine
Document Type: Case study
Length: 3,242 words
Abstract :

Introduction. Gastrointestinal stromal tumors are the most common mesenchymal neoplasms of the gastrointestinal tract. These tumors represent more than 80% of all mesenchymal tumors found in the gastrointestinal tract, though they account for only approximately 3% of all gastrointestinal malignancies. Literature offers case reports, which describe symptomatic gastrointestinal stromal tumors and they generally represent patients with larger tumors. Case report. We present the case of a small gastrointestinal stromal tumor in a 40-year-old man, with associated giant liver hemangioma and fever, and with history of abdominal discomfort and fever. Clinical examination revealed hepatosplenomegaly, palpable mass in the right lower abdomen, and signs of neurofibromatosis type 1 (Morbus von Recklinghausen). Computed tomography revealed a giant tumor in the right lobe of the liver. Magnetic resonance showed abscess in the hemangioma of the liver. An intestinal tumor was incidentally found and excised during surgical laparotomy. An intestinal gastrointestinal stromal tumor was revealed by histopathology and confirmed by immunohistochemistry. Although a multidisciplinary team proposed surgical removal of the liver tumor mass, the surgeons decided to follow up the patient because of a high risk of new intervention. Conclusion. According to the available data, this is a very rare case of small intestinal gastrointestinal stromal tumor, with symptoms of fever and giant abscess in the liver hemangioma. Key words: Gastrointestinal Stromal Tumors; Liver Neoplasms; Hemangioma; Fever; Neurofibromatosis 1; Male; Adult; Signs and Symptoms; Diagnosis Uvod. Gastrointestinalni stromalni tumori najcesce su mezenhimalne neoplazme gastrointestinalnog trakta. Iako ovi tumori cine samo oko 3% svih gastrointestinalnih maligniteta, oni se mogu naci u vise od 80% svih mezenhimskih tumora gastrointestinalnog trakta. U literaturi mozemo pronaci prikaze slucajeva koji opisuju simptomatske gastrointestinalne stromalne tumore vecih dimenzija. Prikaz slucaja. Prikazan je mali gastrointestinalni stromalni tumor kod 40-godisnjeg muskarca, koji je udruzen sa gigantskim hemangiomom jetre i groznicom. Istorija bolesti ovog pacijenta uglavnom se odnosi na trbusne nelagodnosti i groznicu. Klinicki pregled je ukazao na hepatosplenomegaliju, opipljivu masu u donjem desnom delu abdomena, i znake neurofibromatoze tip 1 (Morbus von Recklinghausen). Kompjuterizovanom tomografijom otkriven je veliki tumor (hemangiom) u desnom reznju jetre, dok je magnetnom rezonancijom uoceno prisustvo apscesa u tumoru. Tokom hirurske laparotomije slucajno je otkriven i odstranjen intestinalni tumor, za koji je naknadno histopatoloskom analizom uvtrdeno da pripada gastrointestinalnim stromalnim tumorima. Uprkos predlogu konzilijarnog tima da se tumor jetre hirurski zbrine, hirurzi su odlucili da prate stanje pacijenta zbog visokog rizika od nove intervencije. Zakljucak. Prema dostupnim podacima, ovo je jedinstven slucaj gastrointestinalnog stromalnog tumora tankog creva sa simptomima groznice i prisutnim apscesom u hemangiomu jetre. Kljucne reci: Gastrointestinalni stormalni tumori; Karcinomi jetre; Hemangiomi; Groznica; Neurofibromatoza 1; Musko; Odrasli; Znaci i simptomi; Dijagnoza

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Source Citation
Antic, Vasilije, et al. "Giant liver hemangioma in patient with ileal gastrointestinal stromal tumor/Veliki hemangiom jetre kod pacijenta sa gastrointestinalnim stromalnim tumorom ileuma." Medicinski Pregled, vol. 67, no. 1-2, 2014, p. 55+. Accessed 6 July 2020.
  

Gale Document Number: GALE|A395461945