Isaacs' syndrome (neuromyotonia) associated with peripheral neuropathy/Periferik noropati ile Isaacs sendromu (noromiyotoni) birlikteligi

Citation metadata

Authors: Canan Celik, Sibel Mandiroglu, Halil Ucan and Eser Basak Sevgi
Date: Dec. 2013
From: Turkish Journal of Physical Medicine and Rehabilitation(Vol. 59, Issue 4)
Publisher: Galenos Yayinevi Tic. Ltd.
Document Type: Case study; Report
Length: 2,573 words

Main content

Abstract :

Isaacs's syndrome (neuromyotonia), which is characterized by peripheral nerve hyperexcitability, is a rare condition of spontaneous and continuous muscle fibre activity. This syndrome is associated with myokymia, muscle cramps and stiffness, delayed muscle relaxation after contraction, muscle weakness, and hyperhydrosis. We report two siblings with Isaacs' syndrome associated with peripheral neuropathy gait disturbance, distal muscle weakness, neuromyotonia, muscle spasms, myokymia and hyperhydrosis. In both patients, neuromyotonic discharges were recorded by needle electromyography and axonal sensorimotor peripheral neuropathy was diagnosed electrophysiologically. In this study, a rare case of Isaacs'syndrome (neuromyotonia) associated with peripheral neuropathy is emphasized. Key Words: Isaacs' syndrome, neuromyotonia, peripheral neuropathy Isaacs Sendromu (noromiyotoni), spontan ve surekli kas lif aktivitesi ile ortaya cikan periferik sinirlerin hipereksitabilitesi ile karakterize, nadir gorulen bir klinik durumdur. Bu sendrom miyokimi, kas kramplari ve katiligi, kontraksiyon sonrasi kas gevsemesinde gecikme ve terleme artisi ile iliskilidir. Biz yuruyus bozuklugu, distal kas gucsuzlugu, noromiyotoni, kas spazmlari, miyokimi ve asiri terleme ile karakterize, periferik noropati ile birlikte gorulen Isaacs Sendromlu iki kardes olguyu sunmayi amacladik. Her iki olgumuzda igne elektromiyografisinde noromiyotonik desarjlar ve elektrofizyolojik olarak aksonal tipte sensorimotor periferik noropati tanisi mevcuttu. Bu calismada, periferik noropati ile iliskili Isaacs Sendromu'nun (noromiyotoni) nadir gorulen birlikteligine dikkat cekilmektedir. Anahtar Kelimeler: Isaacs sendromu, noromiyotoni, periferik noropati

Source Citation

Source Citation
Celik, Canan, et al. "Isaacs' syndrome (neuromyotonia) associated with peripheral neuropathy/Periferik noropati ile Isaacs sendromu (noromiyotoni) birlikteligi." Turkish Journal of Physical Medicine and Rehabilitation, vol. 59, no. 4, 2013, p. 353+. Accessed 4 Dec. 2020.
  

Gale Document Number: GALE|A415443409