Excessive refined carbohydrates and scarce micronutrients intakes increase inflammatory mediators and insulin resistance in prepubertal and pubertal obese children independently of obesity

Citation metadata

Authors: Mardia Lopez-Alarcon, Otilia Perichart-Perera, Samuel Flores-Huerta, Patricia Inda-Icaza, Maricela Rodriguez-Cruz and Andrea Armenta-Alvarez
Date: Annual 2014
From: Mediators of Inflammation
Publisher: Hindawi Limited
Document Type: Report
Length: 4,210 words

Main content

Abstract :

Background. Low-grade inflammation is the link between obesity and insulin resistance. Because physiologic insulin resistance occurs at puberty, obese pubertal children are at higher risk for insulin resistance. Excessive diets in refined carbohydrates and saturated fats are risk factors for insulin resistance, but calcium, magnesium, vitamin-D, and the omega-3 fatty acids likely protect against inflammation and insulin resistance. Objective. To analyze interactions among dietary saturated fat, refined carbohydrates, calcium, magnesium, vitamin D, and omega-3 fatty acids on the risk of inflammation and insulin resistance in a sample of prepubertal and pubertal children. Methods. A sample of 229 children from Mexico City was analyzed in a cross-sectional design. Anthropometric measurements, 24h recall questionnaires, and blood samples were obtained. Serum insulin, glucose, calcium, magnesium, 25-OHD3, C-reactive protein, leptin, adiponectin, and erythrocytes fatty acids were measured. Parametric and nonparametric statistics were used for analysis. Results. While mean macronutrients intake was excessive, micronutrients intake was deficient (P

Source Citation

Source Citation
Lopez-Alarcon, Mardia, et al. "Excessive refined carbohydrates and scarce micronutrients intakes increase inflammatory mediators and insulin resistance in prepubertal and pubertal obese children independently of obesity." Mediators of Inflammation, 2014. Accessed 8 Mar. 2021.
  

Gale Document Number: GALE|A424006614