Tapia's syndrome secondary to metastatic prostate cancer

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Authors: Zahide Yilmaz, Gokhan Duygulu and Rabia Terzi
Date: September-October 2015
From: Neurology India(Vol. 63, Issue 5)
Publisher: Medknow Publications and Media Pvt. Ltd.
Document Type: Clinical report
Length: 939 words

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Byline: Zahide. Yilmaz, Gokhan. Duygulu, Sehnaz. Kilic, Rabia. Terzi


A concurrent extra-cranial involvement of the recurrent laryngeal and the hypoglossal nerves is known as Tapia's syndrome, which was first described in 1904 by Garcia Tapia.[sup][1] Symptoms include ipsilateral paralysis of the vocal cords and tongue. Hoarseness, dysphagia, dysarthria, and dyspnea may develop depending upon the level of involvement of these nerves. Although rare, it can complicate general anesthesia with endotracheal intubation. Tumors, trauma, and surgery are among the rare causes of Tapia's syndrome. We report a case of Tapia's syndrome developing due to the presence of skull base metastasis of prostate cancer.

A 61-year-old male patient was referred to us with complaints of dysphagia and hoarseness that was present for the last 2 weeks. The patient's medical history did not include any specific features, except for essential hypertension. The neurological examination showed atrophy and fasciculation in the right half of the tongue. The tongue was deviated to the right due to the involvement of the right hypoglossal nerve [Figure 1]. The ear-nose-throat examination revealed a right vocal cord paresis. The remaining cranial nerve and neurological examination were normal. The routine hemogram and biochemical blood analysis were normal.{Figure 1}

Computed tomography (CT) scan of the temporal bone showed a lytic destructive lesion involving the right half of the occipital bone at the level of the foramen magnum and the right half of the C1...

Source Citation

Source Citation
Yilmaz, Zahide, et al. "Tapia's syndrome secondary to metastatic prostate cancer." Neurology India, vol. 63, no. 5, Sept.-Oct. 2015, p. 782. Accessed 27 Oct. 2021.

Gale Document Number: GALE|A431689295