Central pancreatectomy in surgical treatment of pancreatic insulinoma--a case report /Centralna pankreatektomija uhirurskom tretmanu insulinoma pankreasa--prikaz slucaja

Citation metadata

Authors: Uros Milosevic, Aleksandar Gluhovic, Dorde Milosevic, Nebojsa Budakov and Pavle Milosevic
Date: March-April 2017
From: Medicinski Pregled(Vol. 70, Issue 3-4)
Publisher: Drustvo Lekara Vojvodine
Document Type: Case study
Length: 1,930 words

Main content

Abstract :

Introduction. Insulinomas are the most common pancreatic neuroendocrine tumors. They are typically small solitary tumors and in most cases they are benign intrapancreatic lesions. Indications for central pancreatectomy in modern surgery are limited. Historically, this surgical technique has been predominantly used for pancreatic trauma and chronic pancreatitis. Currently, it is reserved for selective management of benign lesions located in the neck and the body of the pancreas. Case Report. We presented a case of a successful surgical treatment of insulinoma located in the pancreatic body. We discussed the diagnosis, localization and surgical management of this uncommon disease. We also discussed the safety and effectiveness of central pancreatectomy in the treatmant of benign lesions of the pancreatic body. Conclusion. Insulinomas are rare pancreatic neuroendocrine tumors presenting with hypoglycemic symptoms. Surgical removal through enucleation or segmental resection of the pancreas is the mainstay of therapy. Central pancreatectomy may preserve endocrine and exocrine function, as well as the immunological role of the spleen. It is a safe surgical technique with low mortality, but potentially high complication rate. The most common complication is pancreatic fistula. Key words: Pancreatectomy; Insulinoma; Signs and Symptoms; Hypoglycemia; Diagnosis; Pancreatic Neoplasms; Neuroendocrine Tumors; Treatment Outcome; Risk Factors; Pancreatic Fistula Uvod. Insulinomi su najcesci pankreasni neuroendokrini tumori. Insulinomi su po pravilu mali solitarni tumori; u najvecem broju slucajeva predstavljaju dobrocudne intrapankreaticne promene. Indikacije za centralnu pankreatektomiju u modernoj hirurgiji znacajno su suzene. Posmatrano istorijski, ova hirurska metoda koriscena je dominantno u lecenju pankreasnih trauma i hronicnog pankreatitisa. Trenutno se koristi u selektivnom hirurskom lecenju dobrocudnih tumora lokalizovanih u vratu i telu pankreasa. Prikaz slucaja. Prikazujemo slucaj uspesnog hirurskog lecenja insulinoma lokalizovanog u telu pankreasa. U radu razmatramo dijagnozu, lokalizaciju i hirursko lecenje ove retke bolesti. Takode razmatramo bezbednost i efikasnost centralne pankreatektomije u lecenju dobrocudnih promena tela pankreasa. Zakljucak. Insulinomi su retki pankreasni neuroendokrini tumori praceni simptomima hipoglikemije. Hirursko uklanjanje enukleacijom ili segmentalnom resekcijom pankreasa predstavlja glavni nacin lecenja. Centralna pankreatektomija moze sacuvati endokrinu i egzokrinu funkciju pankreasa, kao i imunolosku ulogu slezine. To je bezbedna hirurska tehnika sa niskim mortalitetom, ali sa potencijalno visokom stopom komplikacija. Najcesca komplikacija je pankreasna fistula. Kljucne reci: pankreatektomija; insulinom; znaci i simptomi; hipoglikemija; dijagnoza; neoplazme pankreasa; neuroendokrini tumori; ishod lecenja; faktori rizika; pankreasna fistula

Source Citation

Source Citation
Milosevic, Uros, et al. "Central pancreatectomy in surgical treatment of pancreatic insulinoma--a case report /Centralna pankreatektomija uhirurskom tretmanu insulinoma pankreasa--prikaz slucaja." Medicinski Pregled, vol. 70, no. 3-4, 2017, p. 111+. Accessed 17 Jan. 2021.
  

Gale Document Number: GALE|A493447815