Evaluation of premature newborns with necrotizing enterocolitis/Nekrotizan enterokolitli premature bebeklerin degerlendirilmesi.

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Authors: Hilal Ozkan, Merih Cetinkaya, Nilgun Koksal, Evren Ozboyaci, Ali Ozboyaci and Senay Yapici
Date: Aug. 2010
From: The Journal of Current Pediatrics
Publisher: Galenos Yayinevi Tic. Ltd.
Document Type: Report
Length: 3,646 words

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Abstract :

Introduction: The aim of this study was to evaluate the characteristic features and both early and late term prognosis of premature infants who were followed-up with NEC in the neonatal intensive care unit. Materials and Method: A total of 50 premature infants less than 34 gestational weeks with NEC between January 2005 and December 2009 were included to this study and the characteristic features, clinical and laboratory findings, and prognosis of these infants were evaluated. Results: In this study, 15 infants (30%) had stage 1, 21 infants (42%) had stage 2 and 14 infants (28%) had stage 3 NEC. The incidence of NEC was 7.5% (20/568). The mean gestational age and birth weight of infants who developed NEC were 29 [+ or -] 2.2 weeks and 1142 [+ or -] 300 grams, respectively. The mean onset of NEC was 18.5 [+ or -] 8.1 days. There was hypoxic birth history in 64% of infants and the ratio of breastfed infants was 54%. There was a positive blood culture in 36% of infants with NEC. Surgery was performed in 8 infants with stage 3 NEC, whereas the other infants responded well to medical treatment. The mortality rate was 12% and feeding problems and malabsorption were found to be the most common early and late term problems in infants who survived. Conclusions: NEC is one of the serious problems in premature infants. The mortality and frequency of NEC was decreased with the improvements in the Neonatal Intensive Care. The most important etiological factors were prematurity, hypoxia and enteral feeding. Key words: Prematurity, necrotizing enterocolitis, prognosis Giris: Bu calismanin amaci yenidogan yogun bakim unitesinde nekrotizan enterokolit (NEK) ile izlenmis olan premature bebeklerin karakteristik ozellikleriyle kisa ve uzun donem sonuclarinin degerlendirilmesidir. Gerec ve Yontem: Calismaya Ocak 2005 ile Aralik 2009 yillari arasinda yenidogan yogun bakim unitemizde yatarak takip edilen gestasyon yasi [less than or equal to] 34 hafta olan ve NEK tanisi alan 50 premature bebek alindi ve bu bebeklerin karakteristik ozellikleri, klinik ve laboratuvar bulgulari ve prognozlari degerlendirildi. Bulgular: Calismaya alinan premature bebeklerin 15'inde (%30) evre 1, 21 (%42) tanesinde evre 2 ve 14 (%28) tanesinde evre 3 NEK mevcuttu. NEK insidansi %7,5 (50/658) idi. NEK gelisen bebeklerin ortalama gestasyon yaslarinin ve dogum agirliklarinin, sirasiyla 29 [+ or -] 2,2 hafta ve 1142 [+ or -] 300 gram oldugu goruldu. Ortalama NEK baslangic zamani 18,5 [+ or -] 8,1 gun idi. Olgularin %64'unde hipoksik dogum oykusunun oldugu saptandi ve anne sutu ile beslenme orani %54 olarak bulundu. NEK'li olgularin %36'sinda kan kulturunde ureme tespit edildi. Evre 3 NEK olan 8 olguda cerrahi tedavi uygulanirken diger olgular medikal tedaviye cevap verdi. Mortalite orani %12 olarak bulundu ve yasayan bebeklerde kisa ve uzun donem en sik sorunlarin sirasi ile beslenme problemleri ve malabsorbsiyon oldugu goruldu. Sonuc: NEK premature bebeklerde gorulen en ciddi sorunlardan biridir. Yenidogan yogun bakimindaki gelismelerle mortalitesi ve sikligi azaltilabilmistir. Etyolojide yer alan en onemli faktorler prematurite, hipoksi ve enteral beslenmedir. Anahtar kelimeler: Prematurite, nekrotizan enterokolit, prognoz

Source Citation

Source Citation
Ozkan, Hilal, et al. "Evaluation of premature newborns with necrotizing enterocolitis/Nekrotizan enterokolitli premature bebeklerin degerlendirilmesi." The Journal of Current Pediatrics, Aug. 2010, pp. 56+. Accessed 7 Aug. 2022.
  

Gale Document Number: GALE|A240017339