The cosmetic benefits of boswellic acid

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Date: Summer 2010
From: Australian Journal of Medical Herbalism(Vol. 22, Issue 2)
Publisher: National Herbalists Association of Australia
Document Type: Report
Length: 544 words
Lexile Measure: 1320L

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Pedretti A, Capezzera R, Zane C, Facchinetti E, Calzavara-Pinton P. 2010. Effects of topical boswellic acid on photo and age damaged skin: clinical, biophysical and echographic evaluations in a double blind randomized split face study. Planta Med 76:6;555-60.

Boswellia serrata is an Ayurvedic herb, and its fragrant gum or resin is commonly used for a number of inflammatory disorders and tumours. The active constituents are pentacyclic triterpenes (with alpha or beta structure) called boswellic acids (BA). Their chief mechanism appears to be their effect on IkappaB kinases with subsequent inhibition of NF-kappa B activation and prevention of TNF-alpha release from activated monocytes. BA also inhibit matrix metalloporeinase protein (MMP) transcription in endothelial cells and fibroblasts. MMP (especially MMP-1) is implicated in dermal damage by cleavage of fibrillar collagen.

BA may be beneficial in the treatment of...

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Gale Document Number: GALE|A232178430