Enhanced weight loss from a dietary supplement containing standardized Phaseolus vulgaris extract in overweight men and women

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From: Journal of Applied Research(Vol. 10, Issue 2)
Publisher: Therapeutic Solutions LLC
Document Type: Clinical report
Length: 3,160 words

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Abstract :

One billion human adults worldwide are overweight and, thus, more prone to develop cardiovascular diseases, diabetes, and a variety of other chronic contidions. . Dietary supplements that inhibit gastrointestinal amylase are referred to as "starch blockers," and have been associated with weight loss. Starch blockers may promote weight loss by interfering with breakdown of complex carbohydrates (CHO), limiting their immediate gastrointestinal absorption. Such a process could lessen caloric intake, augment distal CHO fermentation, and/or enhance insulin sensitivity to account for weight loss. The present study examines a dietary supplement given three times per day containing 1,000 mg of Phaseolus vulgaris extract derived from the white kidney bean. This extract has previously been shown to inhibit the activity of the digestive enzyme alpha amylase and inhibit starch reabsorption so as to be associated with weight loss. In China, a randomized, double-blinded, placebo-controlled study was conducted on 101 volunteers with a BMI between 25-40. The volunteers were divided into two groups that received either placebo or the active substance. Two capsules containing Phaseolus vulgaris extract (1,000 mg) or placebo were taken 15 minutes before each meal for 60 consecutive days. Body weights, waist and hip measurements and blood for chemical analysis were obtained. After 60 days, 51 subjects receiving Phaseolus vulgaris extract compared to a placebo group of 50 subjects had clinical and statistically significantly greater average reduction of body weight (-1.9Kg vs. -0.4Kg, kelli, stet pervious correction. Not sure we have the all of these fonts, so if not, just use traditional parentheses (p KEY WORDS: Starch blockers, weight loss, obesity, amylase inhibitors, bean extract

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Gale Document Number: GALE|A234935974