Intraoral fibro-lipoma: A rare histological variant

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Date: January-April 2012
From: Indian Journal of Oral Sciences(Vol. 3, Issue 1)
Publisher: Medknow Publications and Media Pvt. Ltd.
Document Type: Article
Length: 1,411 words
Lexile Measure: 1440L

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Byline: Pramod. Kumar, Anjali. Naraniya

Lipomas are benign neoplasm of adipocytes, but are rarely seen in oral cavity, representing 1% of all benign tumors. Hence, correct histopathological examination of lipomas is important. Fibro-lipoma is one of the rare variant of the lipoma, and very few cases have been reported in the oral cavity. This article describes a case of 60-year-old female with fibro-lipoma of the buccal mucosa. The diagnosis and differentiation of fibro-lipoma with clinically similar lesions such as fibroma, mucocele, and pleomorphic adenoma are very essential for a correct treatment plan and complete follow-up.


Lipomas are the common benign neoplasm of adipose tissue, but they have been considered very unusual growths in the oral and oropharyngeal region. The first description of oral lipoma was provided by roux in 1848 in a review of alveolar masses, and he referred to it as a 'yellow epulis.' [sup][1]

Oral lipoma occurs with a prevalence rate of 1/5,000 adults. [sup][2] Most of the time, they represents a developmental anomaly, but they can also arise as a result of trauma and rearrangement of chromosomes no. 12q, 13q, and 6p. [sup][1],[3]

They are benign mesenchymal neoplasms, composed of fat cells, usually surrounded by a thin fibrous capsule. [sup][4] Histologically, there are many variants of lipoma; fibro-lipoma is one of the rare variants of lipoma in which neoplastic fat cells are embedded within dense collagen bundles. [sup][5] We report a case of fibro-lipoma in a 60-year-old male.

Case Report

A 60-year-old male patient+ was referred to Department of Oral Pathology and Microbiology, Purvanchal Institute of Dental Sciences, with the chief complaint of long standing growth of left buccal mucosa near the corner of mouth. The growth was first noticed approximately 18 months back, which showed slow and continuous enlargement over past one and half year. The swelling interferes while eating, speaking, and swallowing. There was no past history of trauma. Past medical history, past dental history of the patient was non-contributory. Patient gave a history of bidi smoking occasionally since 20 years.

On General examination, patient was of normal built and height. Vital signs were normal, and...

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Gale Document Number: GALE|A307387291