Ovarian Sertoli-Leydig cell tumor: a rare tumor with atypical presentation

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Publisher: Akshantala Enterprises Private Limited
Document Type: Clinical report
Length: 1,966 words
Lexile Measure: 1210L

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Abstract :

Sertoli-Leydig cell tumor (SLCT) is a rare (less than 0.5%), primary malignant sex cord stromal tumor of ovary, which may present with or without hormonal manifestations. Literature regarding biological behavior during pregnancy and/or puerperium is sparse. We aim to report an androgen producing SLCT, in a 22 year old post partum (8 months) female, who presented with torsion and no clinical features of virilization. The detailed clinicopathological characteristics are presented with a review of relevant literature. Sertoli-Leydig cell tumor, though rare, should be kept as a differential diagnosis in the evaluation of unilateral adnexal mass with features of hyperandrogenemia. To the best of our knowledge, this is possibly the first case of SLCT presenting with torsion in the absence of virilization; inspite of biochemical evidence of androgen excess. KEY WORDS: Sertoli-Leydig cell tumor, androgen, pregnancy, post partum, torsion.

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Gale Document Number: GALE|A362849704