BACKGROUND Students of medical as well as paramedical courses can function as a potential source of reliable information to the lay public regarding organ and body donation. They ultimately can play a key role in motivating the public along these lines ensuring successful implementation of organ donation related programs like the Mrithasanjevani. METHODS The cross-sectional study was done after obtaining clearance from institutional research and ethics committee. The second-year students of Government Medical College, Dental College and Nursing College, Thiruvananthapuram formed the study group. They were given a questionnaire regarding the awareness of organ and body donation. Qualitative and quantitative variables of the responses were then analysed. RESULTS Compared to the BDS and MBBS students, BSc nursing students were well informed of the various aspects of organ donation. One surprising finding observed was a reluctance by some medical students to body donation primarily owing to the disrespect shown to the body on the dissection table, which hurts the sentiments of many aspiring medical personnel. CONCLUSIONS A new wave of awareness has been generated in the society regarding organ and body donation, thanks to the efforts of governmental and NGO based campaigns, talks, web and media discussions, in recent times. A well aware population of the medical personnel will help to inculcate the concept in the public and motivate them.