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Academic Journals
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From:African Journal of Medical and Health Sciences (Vol. 12, Issue 2) Peer-ReviewedByline: Kaumudee. Pattnaik, Asaranti. Kar, Sabita. Palai, Bibudhendu. Pati, Chandrasekhar. Mohapatra Chronic myeloid leukemia (CML) is a rare hematological malignancy in children. The more common acute lymphoblastic...
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From:Indian Journal of Pathology and Microbiology (Vol. 58, Issue 1) Peer-ReviewedByline: Kim. Vaiphei, Amita. Trehan, Man. Singh Sachdeva, Pankaj. Malhotra A 14-year-old child with acute lymphoblastic leukemia who had completed induction chemotherapy presented with fever and diffuse...
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From:Oman Journal of Ophthalmology (Vol. 4, Issue 1) Peer-ReviewedByline: Mohammad. Ali, Santosh. Honavar Sir, We read with great interest the article by Bandyopadhyay et al . [sup][1] on unilateral optic nerve infiltration as an initial site of relapse in patients with acute...
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From:Drugs & Aging (Vol. 28, Issue 9) Peer-ReviewedThe main characteristic of acute lymphoblastic leukaemia (ALL) in the elderly is its dismal prognosis. However, other than a lower incidence of T-cell ALL and a greater likelihood of unfavourable chromosomal...
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From:Indian Journal of Ophthalmology (Vol. 55, Issue 3) Peer-ReviewedByline: Neeraj. Wadhwa, Rajpal. Vohra, Dinesh. Shrey, V. Iyer, Satpal. Garg Ocular manifestations form a part of the spectrum of varied clinical presentations in leukemias. Most of the ophthalmic manifestations are...
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From:Pharmacogenomics (Vol. 7, Issue 5) Peer-ReviewedAuthor(s): M Elske van den Akker-van Marle 1 , David Gurwitz 2 3 , Symone B Detmar 1 , Christine M Enzing 1 , Michael M Hopkins 4 , Emma Gutierrez de Mesa 2 , Dolores Ibarreta 2 Keywords: 6-mercaptopurine; acute...
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From:Archives of Disease in Childhood (Vol. 89, Issue 4) Peer-ReviewedIntroduction: New trends for the treatment of childhood acute myeloblastic and lymphoblastic leukaemia (AML, ALL) include more aggressive schedules whose effects on the immunisation status remain unknown. Method: As...
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From:Science (Vol. 246, Issue 4937) Peer-ReviewedAcute lymphoblastic leukemia (ALL) of the non-T type is the most common leukemia in children. A living (in vivo) animal model for studying the growth and progression of ALL was devised using a special strain of mice....
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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Rita Simone 1 , 2 , Claudya Tenca 1 , Franco Fais 1 , Matteo Luciani 3 , Giulio De Rossi 3 , Giampaola Pesce 4 , Marcello Bagnasco 4 , Daniele Saverino 1 , * Introduction Acute lymphoblastic leukemia...
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From:PLoS ONE (Vol. 7, Issue 9) Peer-ReviewedAuthor(s): Hauke Rühs 1 , Achim Becker 1 , Anne Drescher 1 , John C. Panetta 2 , Ching-Hon Pui 3 , Mary V. Relling 2 , Ulrich Jaehde 1 , * Introduction Methotrexate (MTX) is a folate analogue which has been used...
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From:Nature Medicine (Vol. 22, Issue 4) Peer-ReviewedPhosphatase and tensin homolog (PTEN) is a negative regulator of the phosphatidylinositol 3-kinase (PI3K) and protein kinase B (AKT) signaling pathway and a potent tumor suppressor in many types of cancer. To test a...
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From:Indian Journal of Pathology and Microbiology (Vol. 60, Issue 4) Peer-ReviewedByline: Shashi. Bansal, Upendra. Sharma, Akansha. Jain, Richa. Sharma, Bhargav. Yagnik B-lineage acute lymphoblastic leukemia (B-ALL) is an aggressive neoplasm of B-lymphocyte precursors that express the pan B-cell...
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From:Avicenna Journal of Medical Biotechnology (Vol. 11, Issue 1) Peer-ReviewedBackground: Archived bone marrow aspirate slides are almost infinite, readily available resource of biospecimens that enable retrospective molecular investigations of diseases. RNAs obtained from slides has limitations...
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From:Archives of Disease in Childhood (Vol. 85, Issue 4) Peer-ReviewedAbstract Aims--To examine the clinical and biological features of acute lymphoblastic leukaemia in children with Down's syndrome (DS), to compare their survival with other children, and to determine if entry to...
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From:PLoS ONE (Vol. 8, Issue 9) Peer-ReviewedWe previously reported that fenretinide (4-HPR) was cytotoxic to acute lymphoblastic leukemia (ALL) cell lines in vitro in association with increased levels of de novo synthesized dihydroceramides, the immediate...
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From:PLoS ONE (Vol. 7, Issue 5) Peer-ReviewedBackground Relapses occur in about 20% of children with acute lymphoblastic leukemia (ALL). Approximately one-third of these children can be cured. Their risk for late effects is high because of intensified...
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From:PLoS ONE (Vol. 11, Issue 3) Peer-ReviewedDespite recent increases in the cure rate of acute lymphoblastic leukemia (ALL), adult ALL remains a high-risk disease that exhibits a high relapse rate. In this study, we found that the histone demethylase...
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From:PLoS ONE (Vol. 11, Issue 8) Peer-ReviewedIn this study we sought to identify genetic factors associated with the presenting white blood cell (WBC) count in B-precursor acute lymphoblastic leukemia (BP-ALL). Using ETV6-RUNX1-positive BP-ALL patient samples, a...
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From:Molecular Diagnosis & Therapy (Vol. 13, Issue 6) Peer-ReviewedA 61-year-old woman with multiple myeloma developed acute lymphoblastic leukemia (ALL) with mixed-lineage leukemia gene (MLL) rearrangement after receiving cyclophosphamide and melphalan [durations of therapies not...
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From:Reactions Weekly (Issue 1285)[S] A 2.5-year-old boy with acute lymphoblast leukaemia (ALL) developed pulmonary tuberculosis following treatment with dexamethasone [dosage and duration of therapy to reaction onset not stated]. The boy was...