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Academic Journals
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From:Science (Vol. 261, Issue 5117) Peer-ReviewedExperimental systemic lupus erythematosus (SLE) can be induced in mice by immunization with a human monoclonal antibody to DNA that bears a common idiotype (16/6Id). These mice generate antibodies to 16/6Id, antibodies...
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From:Journal of Immunology Research (Vol. 2018) Peer-ReviewedObjective. To investigate the fetal and maternal outcomes as well as predictors of APOs in women with SLE who conceived when the disease was stable, the so-called "planned pregnancy." Methods. A retrospective...
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From:Acta Clinica Belgica (Vol. 66, Issue 3) Peer-ReviewedDear Editor, Mondor's disease is characterized by phlebitis or superficial thrombophlebitis of the anterior and lateral chest walls and involves the lateral thoracic, thoracoepigastric or superior epigastric veins...
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From:Journal of Cardiovascular Echography (Vol. 30, Issue 4) Peer-ReviewedByline: G. Kiran, J. Shashivardhan, P. Chandrasekhar Antiphospholipid syndrome (APLS) is characterized by recurrent thrombosis. We report the case of a 36-year-old male who had acute right-sided ischemic stroke and...
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From:PLoS ONE (Vol. 10, Issue 4) Peer-ReviewedBackground Retinal vein occlusion (RVO) is a common retinal vascular disease and it is one of the most frequently reported causes of visual damage and blindness in the elderly. The current study investigated the...
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From:Clinical Chemistry (Vol. 45, Issue 11) Peer-ReviewedBackground: We report the first two-site, "sandwich type" expression immunoassay using as a label an expressible DNA fragment encoding firefly luciferase. Methods: The DNA label consisted of a T7 RNA polymerase...
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From:Clinical Chemistry (Vol. 45, Issue 4) Peer-ReviewedBackground: The [beta]-core fragment of human chorionic gonadotropin (hCG[beta]cf), also termed "[beta]-core" and urinary gonadotropin peptide (UGP), has been reported to be present in the urine of healthy women and to...
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From:Bulletin of the World Health Organization (Vol. 95, Issue 3) Peer-ReviewedPassive immunization is the transfer of antibodies and occurs naturally during pregnancy. The transplacental transfer of maternal antibodies to the fetus can protect the infant from many infectious diseases for the first...
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From:Clinical Chemistry (Vol. 51, Issue 1) Peer-ReviewedBackground: Pre-[beta]1-HDL, participates in a cyclic process involved in the retrieval of cholesterol from peripheral tissues. Although pre-[beta]1-HDL can be measured by two-dimensional electrophoresis or crossed...
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From:PLoS ONE (Vol. 12, Issue 6) Peer-ReviewedIn resource-limited settings and in the military theater, fresh human whole blood is commonly transfused, but infectious risks are a concern. Sophisticated molecular testing for potential infectious agents in the whole...
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From:Expert Review of Clinical Immunology (Vol. 3, Issue 3) Peer-ReviewedAuthor(s): Ricard Cervera [[dagger]] 1 , Ronald A Asherson 2 Keywords: anticardiolipin antibodies; antiphospholipid antibodies; antiphospholipid syndrome; Asherson's syndrome; catastrophic antiphospholipid...
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From:Clinical Chemistry (Vol. 49, Issue 10) Peer-ReviewedBackground: The diagnosis and management of acute ischemic stroke are limited by the lack of rapid diagnostic assays for use in an emergency setting. Computed tomography (CT) scanning is used to diagnose hemorrhagic...
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From:Ovidius University Annals, Series Physical Education and Sport/Science, Movement and Health (Vol. 21, Issue 2) Peer-ReviewedThrombophilia among pregnant women is a condition that can cause complications in the prepartum and postpartum periods, having as a starting point some protein deficiencies of the body as well as genetic predispositions...
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From:BioMed Research InternationalPeer-ReviewedBackground. According to revised classification criteria of true antiphospholipid antibody syndrome, at least one of three antiphospholipid antibodies should be present on two or more occasions at least 12 weeks apart....
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From:Dermatology Nursing (Vol. 22, Issue 3) Peer-ReviewedThe fields of internal medicine and dermatology have long been intertwined. It is important for the dermatologic nurse to remain up to date on new associations. Several newly reported skin signs of systemic disease are...
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From:Clinical Chemistry (Vol. 54, Issue 3) Peer-ReviewedBACKGROUND: Sensitive methods are needed for biomarker discovery and validation. We tested one promising technology, multiplex proximity ligation assay (PLA), in a pilot study profiling plasma biomarkers in pancreatic...
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From:Clinical Chemistry (Vol. 44, Issue 3) Peer-ReviewedThe presence of human cardiac troponin I (hcTnI) in serum is considered to be a highly specific biochemical marker of acute myocardial infarction. To better understand the antigenic properties of hcTnI, a set of 68...
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From:Pharmaceutical Technology (Vol. 24, Issue 10) Peer-ReviewedThe Last Hurdle for Clinically Successful Therapeutic Antibodies Monoclonal antibodies have numerous potential applications as therapeutics. As target-specific drugs, they should cause fewer side effects than many...
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From:Indian Journal of Dental Advancements (Vol. 2, Issue 1) Peer-ReviewedTumour markers are substances that are produced either by the tumour itself or by the body in response to the presence of cancer or certain benign conditions that can aid in the diagnosis of cancer. the subject of...
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From:Clinical Chemistry (Vol. 48, Issue 7) Peer-ReviewedBackground: Measurement of cardiac natriuretic peptides or their precursors in plasma appears promising in the diagnosis of heart failure. However, the currently available assays to measure pro-B-type natriuretic...