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Academic Journals
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From:Pharmacogenomics (Vol. 12, Issue 3) Peer-ReviewedAuthor(s): Nader Perroud [[dagger]] 5 , Guido Bondolfi 1 , Rudolf Uher 2 , Marianne Gex-Fabry 1 , Jean-Michel Aubry 1 , Gilles Bertschy 3 , Alain Malafosse 1 4 , Markus Kosel 1 KEYWORDS : 5-HTR1B ; ABCB1 ;...
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From:Journal of Family Practice (Vol. 49, Issue 10) Peer-ReviewedTreatment of depression--newer pharmacotherapies. Summary, evidence report/technology assessment: number 7. Rockville, Md: Agency for Health Care Policy and Research; 1999. * BACKGROUND In 1993 the Agency for Health...
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From:Emergency Medicine Journal (Vol. 18, Issue 4) Peer-ReviewedAbstract Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical presentation and...
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From:Psychiatric Times (Vol. 29, Issue 6) Peer-ReviewedMany psychiatric disorders are accompanied by disturbance of sleep. In addition to resolving sleep-related symptoms through their primary therapeutic effects, many psychiatric medications have secondary effects on sleep...
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From:British Medical Journal (Vol. 326, Issue 7397) Peer-ReviewedA collection is just about to be published of the existential poetry of Donald Rumsfeld, the United States defence secretary. He looks set to join Yogi Berra and Sam Goldwyn as a man with a genius for producing sayings...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 8)A new study published in the Archives of General Psychiatry, investigating whether the use of benzodiazepines, antidepressants, or multiple concomitant antipsychotics is linked to increased mortality among hospitalized...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 6)A large prospective cohort study found no strongly increased risk of major malformations, including cardiovascular defects, among infants exposed to antidepressants during the first trimester of pregnancy. The authors...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 7)A prospective controlled study has found that 6-month-old infants who were exposed prenatally to antipsychotic medications scored significantly lower than other infants on a standard test of neuromotor performance. The...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 7)Combination antidepressant therapy has become a popular strategy to manage patients without a satisfactory response to monotherapy. Venlafaxine (Effexor), with a dual mechanism of inhibiting both serotonin and...
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From:Physical Therapy (Vol. 79, Issue 2) Peer-ReviewedThapa PB, Gideon P, Cost TW, et al (Division of Pharmacoepidemiology, Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tenn; Cost Consulting, Nashville, Tenn; Pharmaceutical...
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From:Skeptic (Altadena, CA) (Vol. 17, Issue 2)FOR PEOPLE SATISFIED WITH THEIR STANDARD depression treatments, debunking myths about them may be troubling. Many depressed people, for example, report that their antidepressants have been effective for them, and they...
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From:Expert Review of Neurotherapeutics (Vol. 11, Issue 7) Peer-ReviewedAuthor(s): Ariel Miller [[dagger]] 1 , Hillel Pratt 2 , Randolph B Schiffer 3 Keywords : cerebellum; cortico-pontine-cerebellar circuit; dextromethorphan/quinidine; event-related potentials; involuntary...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 3)In a study using growth mixture modeling (GMM), investigators reanalyzed seven randomized double-blind trials of the serotonin norepinephrine reuptake inhibitor (SNRI) duloxetine (Cymbalta) versus placebo and comparator...
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From:Gut (Vol. 52, Issue 4) Peer-ReviewedSystematic reports of antidepressant use in irritable bowel syndrome (IBS) first appeared in the medical literature three decades ago. Recent meta-analyses of the cumulative controlled experience confirm the efficacy of...
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From:Consultant (Vol. 37, Issue 8) Peer-ReviewedAntidepressants can be used in treating recurrent migraine with major depression or panic disorder. Medical data indicate that tricyclics are efficacious in treating migraine and depression. This is significant since...
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From:Pharmacogenomics (Vol. 12, Issue 6) Peer-ReviewedAuthor(s): Valery Elie 1 , Tiphaine de Beaumais 1 , May Fakhoury 1 , Evelyne Jacqz-Aigrain [[dagger]] 2 KEYWORDS : adverse drug reactions; antidepressants; immunosuppressants; mercaptopurine; metabolomics;...
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From:Psychiatric Times (Vol. 29, Issue 4) Peer-ReviewedIn a recent interview on 60 Minutes, Harvard psychologist Irving Kirsch, PhD, commented, "the difference between the effect of a placebo and the effect of an antidepressant is minimal for most people." (1) However, a...
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From:The Brown University Psychopharmacology Update (Vol. 23, Issue 7)A 25-week controlled trial conducted at nursing homes in Norway has found that patients with dementia and neuropsychiatric symptoms who discontinued antidepressant treatment showed a significant increase in depressive...
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From:Consultant (Vol. 40, Issue 11) Peer-ReviewedBecause the incidence of depression is increasing--especially among the elderly--you can expect to encounter and treat more patients with this condition. A multitude of pharmacologic therapies is available, including...
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From:British Medical Journal (Vol. 319, Issue 7213) Peer-ReviewedGPs should become familiar with one or two antidepressants from each class EDITOR--Livingston and Livingston cast a sceptical eye over the newer antidepressants in relation to the treatment needs of older people with...