Search Results

• • 16,302 

    Academic Journals

  • Sort by: sorttype.publication.date.desc Newest sorttype.publication.date.asc Oldest sorttype.relevance Relevance

• Select Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

  1

  Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

  Authors:Alice Newey, Beatrice Griffiths, Justine Michaux, Hui Song Pak, Brian J. Stevenson, Andrew Woolston, et al.From:Journal for ImmunoTherapy of Cancer (Vol. 7, Issue 1) Peer-Reviewed

  Nov. 18, 20197,310 words Article 1480LBackground Patient derived organoids (PDOs) can be established from colorectal cancers (CRCs) as in vitro models to interrogate cancer biology and its clinical relevance. We applied mass spectrometry (MS)...
• Select Research from Sichuan University in the Area of Biological Factors Described

  2

  Research from Sichuan University in the Area of Biological Factors Described

  From:Obesity, Fitness & Wellness Week

  Mar. 31, 2012358 words Brief article 1850LAccording to the authors of recent research from Chengdu, People's Republic of China, "Advances in novel tumor-associated antigen (TAA) screening strategy have accelerated the identification and characterization of...
• Select Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.

  3

  Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.

  Authors:Monique E. Verhaegen, Paul W. Harms, Julia J. Van Goor, Jacob Arche, Matthew T. Patrick, Dawn Wilbert, et al.From:Journal of Clinical Investigation (Vol. 132, Issue 7) Peer-Reviewed

  Apr. 1, 20224,150 words Report 1570LMerkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer that frequently carries an integrated Merkel cell polyomavirus (MCPyV) genome and expresses viral transforming antigens (TAgs). MCC tumor cells also...
• Select New insights into antigen specific immunotherapy for chronic myeloid leukemia

  4

  New insights into antigen specific immunotherapy for chronic myeloid leukemia

  Authors:Yangqiu Li, Chen Lin, and Christian A SchmidtFrom:Cancer Cell International (Vol. 12, Issue 1) Peer-Reviewed

  Dec. 15, 20126,745 words Report 1590LChronic myeloid leukemia (CML) is a stem cell disease in which BCR/ABL plays an important role as an oncoprotein and a molecular and immunogenic target. Despite the success of targeted therapy using tyrosine kinase...
• Select Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.

  5

  Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.

  Authors:Aviyah Peri, Erez Greenstein, Michal Alon, Joy A. Pai, Tamir Dingjan, Shlomit Reich- Zeliger, et al.From:Journal of Clinical Investigation (Vol. 131, Issue 20) Peer-Reviewed

  Oct. 15, 202112,726 words Report 1400LNeoantigens are now recognized drivers of the antitumor immune response. Recurrent neoantigens, shared among groups of patients, have thus become increasingly coveted therapeutic targets. Here, we report on the...
• Select Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion.

  6

  Antigen presentation in cancer: insights into tumour immunogenicity and immune evasion.

  Authors:Suchit Jhunjhunwala, Christian Hammer, and Lélia DelamarreFrom:Nature Reviews Cancer (Vol. 21, Issue 5) Peer-Reviewed

  May 202116,295 words Report 1560LImmune checkpoint blockade, which blocks inhibitory signals of T cell activation, has shown tremendous success in treating cancer, although success still remains limited to a fraction of patients. To date, clinically...
• Select New Antineoplastics Findings from Technion-Israel Institute of Technology Discussed [Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy]

  7

  New Antineoplastics Findings from Technion-Israel Institute of Technology Discussed [Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy]

  From:Obesity, Fitness & Wellness Week

  Oct. 29, 2016462 words Report 1370L2016 OCT 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on Drugs and Therapies - Antineoplastics are discussed in a new report. According to news reporting...
• Select Tumor-Infiltrating T Cells Correlate with NY-ESO-1-Specific Autoantibodies in Ovarian Cancer

  8

  Tumor-Infiltrating T Cells Correlate with NY-ESO-1-Specific Autoantibodies in Ovarian Cancer

  Authors:Katy Milne, Rebecca O. Barnes, Adam Girardin, Melanie A. Mawer, Nancy J. Nesslinger, Alvin Ng, et al.From:PLoS ONE (Vol. 3, Issue 10) Peer-Reviewed

  Oct. 15, 20088,574 words Article 1470LBackground Tumor-infiltrating CD8+ T cells are correlated with prolonged progression-free and overall survival in epithelial ovarian cancer (EOC). A significant fraction of EOC patients mount autoantibody responses...
• Select Scientists at University of California Report Research in Mononuclear Phagocyte System

  9

  Scientists at University of California Report Research in Mononuclear Phagocyte System

  From:Obesity, Fitness & Wellness Week

  Apr. 28, 2012262 words Brief article 1330LData detailed in "Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells" have been presented. "The nature and site of tumor-antigen presentation...
• Select Researchers at Swiss Institute of Bioinformatics Target Leukocytes ('Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization)

  10

  Researchers at Swiss Institute of Bioinformatics Target Leukocytes ('Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization)

  From:Obesity, Fitness & Wellness Week

  Dec. 30, 2017579 words Article 1440L2017 DEC 30 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Cell Research - Leukocytes have been presented. According to news reporting out of Lausanne,...
• Select Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes.

  11

  Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes.

  Authors:Minh Ngoc Duong, Efe Erdes, Michael Hebeisen, and Nathalie RuferFrom:Journal for ImmunoTherapy of Cancer (Vol. 7, Issue 1) Peer-Reviewed

  Nov. 5, 20198,788 words Article 1680LBackground Affinity-optimized T cell receptor (TCR)-engineered lymphocytes targeting tumor antigens can mediate potent antitumor responses in cancer patients, but also bear substantial risks for off-target toxicities....
• Select CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer

  12

  CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer

  Authors:Michael A Morse, Deborah A Bradley, Tibor Keler, Robert J Laliberte, Jennifer A Green, Thomas A Davis, et al.From:Expert Review of Vaccines (Vol. 10, Issue 6) Peer-Reviewed

  June 20116,322 words Article 1420LAuthor(s): Michael A Morse [[dagger]] 5 , Deborah A Bradley 1 , Tibor Keler 2 , Robert J Laliberte 3 , Jennifer A Green 3 , Thomas A Davis 3 , Brant A Inman 4 Keywords : bladder cancer; cancer immunotherapy;...
• Select Zhengzhou University Researchers Discuss Research in Cancer (POTN: A Human Leukocyte Antigen-A2 Immunogenic Peptides Screening Model and Its Applications in Tumor Antigens Prediction).

  13

  Zhengzhou University Researchers Discuss Research in Cancer (POTN: A Human Leukocyte Antigen-A2 Immunogenic Peptides Screening Model and Its Applications in Tumor Antigens Prediction).

  From:Obesity, Fitness & Wellness Week

  Oct. 24, 2020500 words Report 1320L2020 OCT 24 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on cancer. According to news reporting out of Zhengzhou, People's Republic of China, by...
• Select Carbohydrate 19.9 antigen serum levels in liver disease

  14

  Carbohydrate 19.9 antigen serum levels in liver disease

  Authors:Gaetano Bertino, Annalisa Maria Ardiri, Giuseppe Stefano Calvagno, Giulia Malaguarnera, Donatella Interlandi, Marco Vacante, et al.From:BioMed Research InternationalPeer-Reviewed

  Annual 20133,702 words Report 1580LBackground. Carbohydrate 19.9 antigen (CA19.9) has been used in the diagnosis and followup of gastrointestinal tumours. The aim of this prospective longitudinal study was the evaluation of CA19.9 levels in patients with...
• Select Functionally different HA-1 specific T cells use the same TRBV7-9: a snake in the grass for T cell receptor transfer studies

  15

  Functionally different HA-1 specific T cells use the same TRBV7-9: a snake in the grass for T cell receptor transfer studies

  Authors:Miranda P. Dierselhuis, Ellen Schrama, Jos Pool, Els C. Blokland, William J. Burlingham, and Els GoulmyFrom:Immunotherapy InsightsPeer-Reviewed

  Nov. 19, 20122,356 words Report 1820LNew developments in cellular adoptive immunotherapy have led to tailor made therapies for cancer patients. One of the latter therapies is tumor antigen-specific T cell receptor (TCR) transfer enabling recognition of,...
• Select Reports Outline Hypersensitivity and Genetics Study Findings from National Jewish Health (Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation)

  16

  Reports Outline Hypersensitivity and Genetics Study Findings from National Jewish Health (Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation)

  From:Obesity, Fitness & Wellness Week

  Jan. 16, 2016330 words Brief article, Repor... 1610L2016 JAN 16 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Immune System Diseases and Conditions. According to news reporting originating in...
• Select Melacine[R]: an allogeneic melanoma tumor cell lysate vaccine

  17

  Melacine[R]: an allogeneic melanoma tumor cell lysate vaccine

  Authors:Jeffrey A. Sosman and Vernon K. SondakFrom:Expert Review of Vaccines (Vol. 2, Issue 3) Peer-Reviewed

  June 1, 200310,864 words Report 1470LCancer vaccines have represented the holy grail of tumor immunology to many. In 2003, there are innumerable approaches to active specific immunotherapy for cancer. The identification of tumor antigens recognized by and...
• Select Cross-priming of cyclin B1, MUC-1 and survivin-specific CD8+T cells by dendritic cells loaded with killed allogeneic breast cancer cells

  18

  Cross-priming of cyclin B1, MUC-1 and survivin-specific CD8+T cells by dendritic cells loaded with killed allogeneic breast cancer cells

  Authors:Hiroaki Saito, Peter Dubsky, Carole Dantin, Olivera J Finn, Jacques Banchereau, and A Karolina PaluckaFrom:Breast Cancer Research (Vol. 8, Issue 6) Peer-Reviewed

  Nov. 27, 20065,469 words Article 1500LIntroduction The ability of dendritic cells (DCs) to take up whole tumor cells and process their antigens for presentation to T cells ('cross-priming') is an important mechanism for induction of tumor specific...
• Select HLA ligandome tumor antigen discovery for personalized vaccine approach

  19

  HLA ligandome tumor antigen discovery for personalized vaccine approach

  Authors:Hans-Georg Rammensee and Harpreet Singh-JasujaFrom:Expert Review of Vaccines (Vol. 12, Issue 10) Peer-Reviewed

  Oct. 20135,494 words Report 1640LAuthor(s): Hans-Georg Rammensee [*] 1 , Harpreet Singh-Jasuja 2 Keywords : antigens; cancer immunotherapy; genome sequencing; HLA ligandome; immunogenicity; immunomonitoring; mutations; T cells; vaccination...
• Select Karolinska Institut Reports Research in Melanomas

  20

  Karolinska Institut Reports Research in Melanomas

  From:Obesity, Fitness & Wellness Week

  Jan. 22, 2011384 words Brief article 1490LA new study, 'T cell recognition of HLA-A2 restricted tumor antigens is impaired by the oncogene HER2,' is now available. "The HER2 oncogene is frequently over-expressed in human cancers and a promising target for...