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    Academic Journals

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• XIAP impairs mitochondrial function during apoptosis by regulating the Bcl-2 family in renal cell carcinoma

  Authors:Chao Chen, Tian Shu Liu, Si Cong Zhao, Wen Zheng Yang, Zong Ping Chen, and Yong YanFrom:Experimental and Therapeutic Medicine (Vol. 15, Issue 5) Peer-Reviewed

  May 20184,361 words Report 1350LEfficient apoptosis requires Bcl-2 family-mediated mitochondrial outer membrane permeabilization (MOMP), which releases pro-apoptotic proteins to the cytosol, activating apoptosis and inhibiting X-linked inhibitor of...

• Researchers at University of Lausanne Have Published New Data on Apoptosis

  From:Obesity, Fitness & Wellness Week

  Mar. 31, 2012256 words Brief article 1110LFresh data on Apoptosis are presented in the report "Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation. 'Interleukin-1[sz] (IL-1[sz]) is a potent inflammatory cytokine that is usually...

• Research from National Institute of Respiratory Diseases Provides New Insights into Apoptosis

  From:Obesity, Fitness & Wellness Week

  Apr. 28, 2012270 words Brief article, Repor... 1260L"Survivin is an important member of the Inhibitor of Apoptosis Proteins (IAPs) family and has essential roles in apoptosis and cell cycle progression. This gene is commonly upregulated in human cancer and provides an...

• Mercurio y muerte celular

  Author:Salvador Penna VideauFrom:Geominas (Vol. 39, Issue 54) Peer-Reviewed

  Apr. 20113,992 words Article Existen respuestas adaptativas a las lesiones celulares que incluyen la necrosis y la apoptosis o muerte celular programada. Estas difieren en sus patrones morfológicos y en las consecuencias que generan en los tejidos...

• Researchers at University of the District of Columbia Target Pancreatic Cancer

  From:Obesity, Fitness & Wellness Week

  Mar. 10, 2012305 words Brief article 1250LResearchers detail in "Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells," new data in Pancreatic Cancer. "Pancreatic cancer is the fourth leading cause of cancer-related deaths in...

• Bax expression measured by AQUAnalysis is an independent prognostic marker in oral squamous cell carcinoma

  Authors:Pinaki Bose, Alexander C Klimowicz, Elizabeth Kornaga, Stephanie K Petrillo, T Wayne Matthews, Shamir Chandarana, et al.From:BMC Cancer (Vol. 12, Issue 1) Peer-Reviewed

  Aug. 1, 20126,247 words Report 1410LBackground Resistance to apoptosis is a hallmark of cancer and proteins regulating apoptosis have been proposed as prognostic markers in several malignancies. However, the prognostic impact of apoptotic markers has...

• Successful allogeneic hematopoietic stem cell transplantation in a boy with X-linked inhibitor of apoptosis deficiency presenting with hemophagocytic lymphohistiocytosis: a case report

  Authors:Ming-Yan Jiang, Xia Guo, Shu-Wen Sun, Qiang Li, and Yi-Ping ZhuFrom:Experimental and Therapeutic Medicine (Vol. 12, Issue 3) Peer-Reviewed

  Sept. 20162,689 words Case study 1490LX-linked inhibitor of apoptosis (XIAP) deficiency, also known as X-linked lymphoproliferative syndrome type 2 (XLP2), is a rare inherited primary immunodeficiency resulting from the XIAP (also known as BIRC4) mutation....

• Inhibitor of apoptosis proteins

  From:Nature Reviews Drug Discovery (Vol. 11, Issue 2) Peer-Reviewed

  Feb. 2012133 words Report 1430LInhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic proteins that promote the survival and proliferation of cancer cells by interfering with the activation of caspases. Because they are overexpressed in...

• X-linked inhibitor of apoptosis positive nuclear labeling: a new independent prognostic biomarker of breast invasive ductal carcinoma

  Authors:Yutao Zhang, Jianhua Zhu, Yun Tang, Feng Li, Hongyuan Zhou, Bofang Peng, et al.From:Diagnostic Pathology (Vol. 6) Peer-Reviewed

  June 7, 20114,500 words Report 1430LBackground It's well recognized that X-linked inhibitor of apoptosis (XIAP) was the most potent caspase inhibitor and second mitochondria-derived activator of caspase (Smac) was the antagonist of XIAP. Experiments in...

• Researchers from Xi'an Jiao Tong University Describe Findings in Lung Cancer

  From:Obesity, Fitness & Wellness Week

  Apr. 28, 2012254 words Brief article 1160L"Apoptosis is a conserved and regulated cell suicide process, the malfunction of which is closely linked with carcinogenesis. Caspases control the induction of apoptosis through an enzymatic cascade that can be...

• MiR-34c induces apoptosis and inhibits the viability of M4e cells by targeting BCL2

  Authors:Rui Li, Hongxia Zhang, and Xiling ZhengFrom:Oncology Letters (Vol. 15, Issue 3) Peer-Reviewed

  Mar. 20183,669 words Report 1350LThe present study aimed to investigate microRNA (miR/miRNA)-34c expression and the association of miR-34c with B cell lymphoma 2 (BCL2) in M4e laryngeal carcinoma cell line. M4e laryngeal carcinoma cells were cultured...

• Geraniin induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro and in vivo

  Authors:Jia Li, Siran Wang, Jimei Yin, and Linna PanFrom:Canadian Journal of Physiology and Pharmacology (Vol. 91, Issue 12) Peer-Reviewed

  Dec. 20135,199 words Clinical report 1410LGeraniin has previously been reported to possess extensive biological activity. In this study, we reported that geraniin is an inhibitor of tumor activity in vitro and in vivo. Geraniin suppressed the proliferation of...

• Capital Medical University Researchers Publish New Data on Thyroid Cancer (SGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways).

  From:Obesity, Fitness & Wellness Week

  Mar. 5, 2022581 words Article 1310L2022 MAR 5 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on thyroid cancer. According to news originating from Capital Medical University by...

• Role of transmembrane tyrosin kinases in dexamethasone induced enhanced phagocytosis of apoptotic cells

  Authors:Laszlo Fesus, Endre Karoly Kristof, and Gabor ZahuczkyFrom:International Journal of Collaborative Research on Internal Medicine & Public Health (Vol. 3, Issue 3) Peer-Reviewed

  Mar. 2011655 words Brief article, Repor... Background: The daily clearance of about 500 billion physiologically dying cells in the human body is performed safely mainly by the mononuclear phagocyte system. At least 10-15% of the cells in most human tissues are...

• Change in contents of biologically active sphingolipids modulating cell growth and survival in hepatoma 27 compared to rat liver

  Authors:E.V. Dyatlovitskaya, A.G. Kandyba, V.A. Kobliakov, and O.G. SomovaFrom:Biochemistry (Moscow) (Vol. 69, Issue 5) Peer-Reviewed

  May 20042,194 words Article 1620LAbstract -- The contents of bioactive sphingolipids (sphingomyelin, ceramide, glucosyl- and lactosylceramides, gangliosides) were studied in rat hepatoma 27 and rat liver. The amounts of sphingomyelin, ceramide, and...

• Research on Apoptosis Discussed by Investigators at Columbia University

  From:Stem Cell Week

  Feb. 25, 2013427 words Report 1650LBy a News Reporter-Staff News Editor at Stem Cell Week -- Research findings on Apoptosis are discussed in a new report. According to news reporting originating in New York City, New York, by NewsRx journalists, research...

• Retracted article: MAVS protects cells from apoptosis by negatively regulating VDAC1

  Authors:Yang Xu, Hui Zhong, and Wei ShiFrom:Molecular and Cellular Biochemistry (Vol. 375, Issue 1-2) Peer-Reviewed

  Mar. 201373 words Brief article 1540LThis article is being retracted due to unauthorized use and inclusion of data, in which the author presented data as if it were his own and without proper acknowledgement. DOI 10.1007/s11010-010-0658-4 Received: 1...

• Aberrant promoter hypermethylation of p21 (WAF1/CIP1) gene and its impact on expression and role of polymorphism in the risk of breast cancer

  Authors:Marjan Askari, Ranbir Chander Sobti, Mohsen Nikbakht, and Suresh C. SharmaFrom:Molecular and Cellular Biochemistry (Vol. 382, Issue 1-2) Peer-Reviewed

  Oct. 20135,607 words Article 1470Lp21 (Waf-1) is a cyclin-dependent kinase inhibitor that plays essential roles in cell growth arrest, terminal differentiation, and apoptosis. Statistically significant difference in the level of methylation of p21/CIP1...

• New Stem Cells Study Results from University of Virginia Health System Described (Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim)

  From:Stem Cell Week

  Aug. 25, 2014446 words Article 1600LBy a News Reporter-Staff News Editor at Stem Cell Week -- Investigators discuss new findings in Stem Cell Research. According to news reporting from Charlottesville, Virginia, by NewsRx journalists, research stated,...

• Anticancer potential of Conium maculatum extract against cancer cells in vitro: Drug-DNA interaction and its ability to induce apoptosis through ROS generation

  Authors:Jesmin Mondal, Ashis Panigrahi, and Anisur Khuda-BukhshFrom:Pharmacognosy Magazine (Vol. 10, Issue 39) Peer-Reviewed

  Aug. 20145,220 words Report 1470LByline: Jesmin. Mondal, Ashis. Panigrahi, Anisur. Khuda-Bukhsh Objective: Conium maculatum extract is used as a traditional medicine for cervix carcinoma including homeopathy. However, no systematic work has so far...