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• The future of dual therapy for hepatitis C virus

  Authors:Francesco Azzaroli, Marco Montagnani, Alberto Porro, Domenico Fiorillo, and Giuseppe MazzellaFrom:Future Virology (Vol. 9, Issue 10)

  Oct. 20146,055 words Report 2060LAuthor(s): Francesco Azzaroli aff1 , Marco Montagnani aff1 , Alberto Porro aff1 , Domenico Fiorillo aff1 , Giuseppe Mazzella [*] aff1 KEYWORDS direct-acting antivirals; hepatitis C virus; interferon; ribavirin;...

• Indolent B-cell lymphomas associated with HCV infection: clinical and virological features and role of antiviral therapy

  Authors:Luca Arcaini, Michele Merli, Stefano Volpetti, Sara Rattotti, Manuel Gotti, and Francesco ZajaFrom:Clinical and Developmental ImmunologyPeer-Reviewed

  September-October 20127,695 words Article 1550LThe association between hepatitis C virus (HCV) infection and B-cell non-Hodgkin's lymphomas (NHL) has been demonstrated by epidemiological studies, in particular in highly endemic geographical areas such as Italy,...

• Chronic inflammatory demyelinating polyneuropathy following treatment with peglated interferon a-2a for chronic hepatitis C virus infection

  Authors:Chang Ying, Han Xue-Mei, Gao Yao, and Liu Song-YanFrom:Neurology India (Vol. 59, Issue 1) Peer-Reviewed

  January-February 20111,088 words Clinical report 1430LByline: Chang. Ying, Han. Xue-mei, Gao. Yao, Liu. Song-yan Sir, The etiopathogenisis of chronic inflammatory demyelinating polyneuropathy (CIDP) is unknown yet. Peglated interferon a-2a is an antiviral biological...

• Cytokine-induced dicing and splicing in the [beta]-cell and the immune response in type 1 diabetes

  Authors:John C. Hutton and Howard W. DavidsonFrom:Diabetes (Vol. 59, Issue 2) Peer-Reviewed

  Feb. 20101,852 words Clinical report 1630LCytokines play a prominent role in mediating the inflammatory response related to injury, infection, and physiological processes from reproduction (1) to suntanning (2). Their impact on the target tissue can be...

• Virus C genotype predisposes to primary hypothyroidism during interferon-[alpha] treatment for chronic hepatitis C

  Authors:Maria Helena Postal Pavan, Elizabeth Joao Pavin, Fernando Lopes Gonzales, Jr., and Denise Engelbrecht Zantut WittmannFrom:The Brazilian Journal of Infectious Diseases (Vol. 15, Issue 5) Peer-Reviewed

  September-October 20114,677 words Article 1660LObjective: The treatment of the chronic hepatitis C (HCV) with [alpha]-interferon is associated with thyroid dysfunction (TD). The aim of this study was to evaluate thyroid function outcome among patients with chronic...

• Pegylated IFN-[alpha]2a and ribavirin in the treatment of hepatitis C

  Authors:Alessio Aghemo, Maria Grazia Rumi, and Massimo ColomboFrom:Expert Review of Anti-infective Therapy (Vol. 7, Issue 8) Peer-Reviewed

  Oct. 20098,170 words Article Author(s): Alessio Aghemo [[dagger]] 1 , Maria Grazia Rumi 2 , Massimo Colombo 3 Keywords: chronic hepatitis C; HCV; PegIFN-[alpha]2a; ribavirin; sustained virological response Hepatitis C virus eradication is...

• News & Views in ... Pharmacogenomics

  From:Pharmacogenomics (Vol. 12, Issue 9) Peer-Reviewed

  Sept. 2011477 words Article 1390LIn honor of the WHO World Hepatitis day 2011, observed 28 July, the Pharmacogenetics for Every Nation Initiative has issued a press release detailing the initial global risk map for response to Hepatitis C therapy....

• Effect of Antiviral Therapy on Hepatitis C Virus Related Glomerulopathy

  Authors:Ghulam Abbas, Shahid Hussain, and Tahir ShafiFrom:Saudi Journal of Kidney Diseases and Transplantation (Vol. 19, Issue 5) Peer-Reviewed

  September-October 20082,646 words Article 1530LByline: Ghulam. Abbas, Shahid. Hussain, Tahir. Shafi To determine the efficacy of antiviral therapy in hepatitis C virus associated glome-rulopathy, we studied 30 patients with HCV-associated glomerulopathy at Sheikh...

• Fetal risks related to the treatment of multiple sclerosis during pregnancy and breastfeeding

  Authors:Simone Ferrero, Francesca Esposito, Stefano Pretta, and Nicola RagniFrom:Expert Review of Neurotherapeutics (Vol. 6, Issue 12) Peer-Reviewed

  Dec. 20067,201 words Report Author(s): Simone Ferrero [[dagger]] 1 , Francesca Esposito 2 , Stefano Pretta 3 , Nicola Ragni 4 Keywords: azathioprine; cyclophosphamide; glatiramer acetate; glucocorticoids; immunoglobulin; interferon-[beta]-1;...

• Multiple sclerosis disease-modifying therapies: adverse effect surveillance and management

  Author:Dean M WingerchukFrom:Expert Review of Neurotherapeutics (Vol. 6, Issue 3) Peer-Reviewed

  Mar. 200610,652 words Article 1440LAuthor(s): Dean M Wingerchuk 1 Keywords : adverse effects; [beta]-interferon; glatiramer acetate; long-term therapy; mitoxantrone; multiple sclerosis; natalizumab Multiple sclerosis (MS) is a lifelong...

• New approaches to rapidly control foot-and-mouth disease outbreaks

  Author:Marvin J. GrubmanFrom:Expert Review of Anti-infective Therapy (Vol. 1, Issue 4) Peer-Reviewed

  Dec. 1, 20037,240 words Report Economically, foot-and-mouth disease is the most important viral-induced livestock disease worldwide. The disease is highly contagious and foot-and-mouth disease virus replicates and spreads extremely rapidly. Recent...

• Biological therapy

  Authors:Timothy Perren and Peter SelbyFrom:British Medical Journal (Vol. 304, Issue 6842) Peer-Reviewed

  June 20, 19922,829 words Article Biological therapy, or treatment with cells or substances produced by cells, is used to treat patients with some types of cancer. Interest in biological therapy began with the explosion of knowledge in molecular biology...

• 3B Actinic keratoses

  From:MPR Pharmacists' Edition (Vol. 6, Issue 4)

  Winter 2012771 words Drug overview 770LALDARA Medicis Rx Immune response modifier. Imiquimod 5%; crm. Indications: Actinic keratoses on face or scalp. Superficial basal cell carcinoma when surgery is impractical (see literature). Adults: [greater...

• Evaluation of factors associated with relapse in telaprevir-based triple therapy for chronic hepatitis C

  Authors:C. Kondo, M. Atsukawa, A. Tsubota, N. Shimada, H. Abe, and Y. AizawaFrom:Journal of Postgraduate Medicine (Vol. 62, Issue 1) Peer-Reviewed

  January-March 20163,949 words Clinical report 1470LByline: C. Kondo, M. Atsukawa, A. Tsubota, N. Shimada, H. Abe, Y. Aizawa Background and Rationale: Most patients with chronic hepatitis C show virological response to telaprevir-based triple therapy, and achieve an...

• Expression of cytokine-mRNA in peripheral blood mononuclear cell of human immunodeficiency virus-1 subtype C infected individuals with opportunistic viral infections from India (South)

  Authors:J. Sachithanandham, V. Ramalingam, J. Raja, O. Abraham, S. Pulimood, and R. KannangaiFrom:Indian Journal of Medical Microbiology (Vol. 34, Issue 1)

  January-March 20162,890 words Article 1770LByline: J. Sachithanandham, V. Ramalingam, J. Raja, O. Abraham, S. Pulimood, R. Kannangai Human immunodeficiency virus (HIV) disease progression is associated with a marked change in the level of plasma cytokines....

• Deciphering the Interleukin 28B Variants That Better Predict Response to Pegylated Interferon-[alpha] and Ribavirin Therapy in HCV/HIV-1 Coinfected Patients

  Authors:Montserrat de Castellarnau, Ester Aparicio, Mariona Parera, Sandra Franco, Cristina Tural, Bonaventura Clotet, et al.From:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 6, 20123,170 words Article 1490LAuthor(s): Montserrat de Castellarnau 1 , Ester Aparicio 1 , Mariona Parera 1 , Sandra Franco 1 , Cristina Tural 2 , Bonaventura Clotet 1 , 2 , Miguel Angel Martínez 1 , * Introduction The combination of pegylated...

• Factors Associated with the Performance of a Blood-Based Interferon-[gamma] Release Assay in Diagnosing Tuberculosis

  Authors:Sally Banfield, Elaine Pascoe, Aesen Thambiran, Aris Siafarikas, and David BurgnerFrom:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 12, 20124,510 words Article 1800LAuthor(s): Sally Banfield 1 , Elaine Pascoe 1 , 5 , Aesen Thambiran 4 , Aris Siafarikas 1 , 2 , 3 , David Burgner 1 , 6 , * Introduction Mycobacterium tuberculosis (MTB) infects over one third of the global...

• AAV2-Mediated Combined Subretinal Delivery of IFN-[alpha] and IL-4 Reduces the Severity of Experimental Autoimmune Uveoretinitis

  Authors:Lichun Tian, Bo Lei, Ju Shao, Lin Wei, Aize Kijlstra, and Peizeng YangFrom:PLoS ONE (Vol. 7, Issue 6) Peer-Reviewed

  June 7, 20124,998 words Article 1670LAuthor(s): Lichun Tian 1 , 2 , Bo Lei 1 , Ju Shao 1 , Lin Wei 1 , Aize Kijlstra 3 , Peizeng Yang 1 , * Introduction Uveitis is a common eye disease [1] and is one of the major causes of visual handicap within the...

• Sequence Heterogeneity in NS5A of Hepatitis C Virus Genotypes 2a and 2b and Clinical Outcome of Pegylated-Interferon/Ribavirin Therapy

  Authors:Ahmed El-Shamy, Ikuo Shoji, Soo-Ryang Kim, Yoshihiro Ide, Susumu Imoto, Lin Deng, et al.From:PLoS ONE (Vol. 7, Issue 2) Peer-Reviewed

  Feb. 2, 20126,290 words Article 1530LAuthor(s): Ahmed El-Shamy 1 , 2 , Ikuo Shoji 1 , Soo-Ryang Kim 3 , Yoshihiro Ide 1 , Susumu Imoto 3 , Lin Deng 1 , Seitetsu Yoon 4 , Takashi Fujisawa 5 , Satoshi Tani 6 , Yoshihiko Yano 7 , Yasushi Seo 7 , Takeshi Azuma...

• Local Applications of Myostatin-siRNA with Atelocollagen Increase Skeletal Muscle Mass and Recovery of Muscle Function

  Authors:Emi Kawakami, Nobuhiko Kawai, Nao Kinouchi, Hiroyo Mori, Yutaka Ohsawa, Naozumi Ishimaru, et al.From:PLoS ONE (Vol. 8, Issue 5) Peer-Reviewed

  May 22, 20134,553 words Article 1470LAuthor(s): Emi Kawakami 1, Nobuhiko Kawai 1, Nao Kinouchi 1, Hiroyo Mori 1, Yutaka Ohsawa 2, Naozumi Ishimaru 3, Yoshihide Sunada 2, Sumihare Noji 4, Eiji Tanaka 1,* Introduction Small interfering RNA (siRNA) can...